Standard
Pulmonary emphysema
MAN2B1 · rs10411619
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Pulmonary emphysema — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Pulmonary emphysema.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Pulmonary emphysema compared to the general population.
Source
Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study
Manichaikul A,
Hoffman EA,
Smolonska J,
Gao W,
Cho MH,
Baumhauer H,
Budoff M,
Austin JH,
Washko GR,
Carr JJ,
Kaufman JD,
Pottinger T
and 22 more — show all
Powell CA,
Wijmenga C,
Zanen P,
Groen HJ,
Postma DS,
Wanner A,
Rouhani FN,
Brantly ML,
Powell R,
Smith BM,
Rabinowitz D,
Raffel LJ,
Hinckley Stukovsky KD,
Crapo JD,
Beaty TH,
Hokanson JE,
Silverman EK,
Dupuis J,
O'Connor GT,
Boezen HM,
Rich SS,
Barr RG
American journal of respiratory and critical care medicine · 2014 · PMID 24383474
Questions about rs10411619
What is rs10411619?
rs10411619 is a single position in the genome, in or near the MAN2B1 gene. Published research associates it with pulmonary emphysema. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10411619 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10411619 come from?
GWAS Catalog, Am J Respir Crit Care Med 2014, PMID:24383474. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants