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Who was studied up to 31,465 European ancestry cases, up to 203,688 European ancestry controls, up to 1,413 African ancestry cases, up to 6,080 African ancestry controls, up to 287 East Asian ancestry cases, up to 7,484 East Asian ancestry controls, up to 61 Hispanic cases, up to 613 Hispanic controls.
The effect
Each copy of the A allele carried 1.11 times the odds of Chronic obstructive pulmonary disease (95% confidence interval 1.08 -1.15); p = 3 × 10−12.
How common The A allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 6, band 6p22.2 — a missense change in BTN2A1.
What each result means
A/ATwo copies of the version the research linked to Chronic obstructive pulmonary disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Chronic obstructive pulmonary disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Chronic obstructive pulmonary disease. This is the starting point the study compared everyone against.
American journal of physiology. Lung cellular and molecular physiology · 2021 · PMID 33909500
Questions about rs13195509
What is rs13195509?
rs13195509 is a single position in the genome, in or near the BTN2A1 gene. Published research associates it with chronic obstructive pulmonary disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs13195509 linked to?
On MyGeneLog this position is linked to Chronic Obstructive Pulmonary Disease (COPD). The research behind each link, and its sources, are set out on that condition page.
Does having rs13195509 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13195509 come from?
GWAS Catalog, American journal of physiology. Lung cellular and molecular physiology 2021, PMID:33909500. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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