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22 matches for
Padyukov L,
showing the first 20.
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Okada Y,
Wu D,
Trynka G,
Raj T,
Terao C,
Ikari K,
Kochi Y,
Ohmura K,
Suzuki A,
Yoshida S,
Graham RR,
Manoharan A
and 83 more — show all
Ortmann W,
Bhangale T,
Denny JC,
Carroll RJ,
Eyler AE,
Greenberg JD,
Kremer JM,
Pappas DA,
Jiang L,
Yin J,
Ye L,
Su DF,
Yang J,
Xie G,
Keystone E,
Westra HJ,
Esko T,
Metspalu A,
Zhou X,
Gupta N,
Mirel D,
Stahl EA,
Diogo D,
Cui J,
Liao K,
Guo MH,
Myouzen K,
Kawaguchi T,
Coenen MJ,
van Riel PL,
van de Laar MA,
Guchelaar HJ,
Huizinga TW,
Dieudé P,
Mariette X,
Bridges SL Jr,
Zhernakova A,
Toes RE,
Tak PP,
Miceli-Richard C,
Bang SY,
Lee HS,
Martin J,
Gonzalez-Gay MA,
Rodriguez-Rodriguez L,
Rantapää-Dahlqvist S,
Arlestig L,
Choi HK,
Kamatani Y,
Galan P,
Lathrop M,
Eyre S,
Bowes J,
Barton A,
de Vries N,
Moreland LW,
Criswell LA,
Karlson EW,
Taniguchi A,
Yamada R,
Kubo M,
Liu JS,
Bae SC,
Worthington J,
Padyukov L,
Klareskog L,
Gregersen PK,
Raychaudhuri S,
Stranger BE,
De Jager PL,
Franke L,
Visscher PM,
Brown MA,
Yamanaka H,
Mimori T,
Takahashi A,
Xu H,
Behrens TW,
Siminovitch KA,
Momohara S,
Matsuda F,
Yamamoto K,
Plenge RM
RACI consortium · GARNET consortium
Nature · 2014 · PMID 24390342 · open access
12 pages+
FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease
Saevarsdottir S,
Olafsdottir TA,
Ivarsdottir EV,
Halldorsson GH,
Gunnarsdottir K,
Sigurdsson A,
Johannesson A,
Sigurdsson JK,
Juliusdottir T,
Lund SH,
Arnthorsson AO,
Styrmisdottir EL
and 34 more — show all
Gudmundsson J,
Grondal GM,
Steinsson K,
Alfredsson L,
Askling J,
Benediktsson R,
Bjarnason R,
Geirsson AJ,
Gudbjornsson B,
Gudjonsson H,
Hjaltason H,
Hreidarsson AB,
Klareskog L,
Kockum I,
Kristjansdottir H,
Love TJ,
Ludviksson BR,
Olsson T,
Onundarson PT,
Orvar KB,
Padyukov L,
Sigurgeirsson B,
Tragante V,
Bjarnadottir K,
Rafnar T,
Masson G,
Sulem P,
Gudbjartsson DF,
Melsted P,
Thorleifsson G,
Norddahl GL,
Thorsteinsdottir U,
Jonsdottir I,
Stefansson K
Nature · 2020 · PMID 32581359
12 pages+
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis
Ishigaki K,
Sakaue S,
Terao C,
Luo Y,
Sonehara K,
Yamaguchi K,
Amariuta T,
Too CL,
Laufer VA,
Scott IC,
Viatte S,
Takahashi M
and 78 more — show all
Ohmura K,
Murasawa A,
Hashimoto M,
Ito H,
Hammoudeh M,
Emadi SA,
Masri BK,
Halabi H,
Badsha H,
Uthman IW,
Wu X,
Lin L,
Li T,
Plant D,
Barton A,
Orozco G,
Verstappen SMM,
Bowes J,
MacGregor AJ,
Honda S,
Koido M,
Tomizuka K,
Kamatani Y,
Tanaka H,
Tanaka E,
Suzuki A,
Maeda Y,
Yamamoto K,
Miyawaki S,
Xie G,
Zhang J,
Amos CI,
Keystone E,
Wolbink G,
van der Horst-Bruinsma I,
Cui J,
Liao KP,
Carroll RJ,
Lee HS,
Bang SY,
Siminovitch KA,
de Vries N,
Alfredsson L,
Rantapää-Dahlqvist S,
Karlson EW,
Bae SC,
Kimberly RP,
Edberg JC,
Mariette X,
Huizinga T,
Dieudé P,
Schneider M,
Kerick M,
Denny JC,
Matsuda K,
Matsuo K,
Mimori T,
Matsuda F,
Fujio K,
Tanaka Y,
Kumanogoh A,
Traylor M,
Lewis CM,
Eyre S,
Xu H,
Saxena R,
Arayssi T,
Kochi Y,
Ikari K,
Harigai M,
Gregersen PK,
Yamamoto K,
Louis Bridges S Jr,
Padyukov L,
Martin J,
Klareskog L,
Okada Y,
Raychaudhuri S
BioBank Japan Project
Nature genetics · 2022 · PMID 36333501
12 pages+
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets
Zhao JH,
Stacey D,
Eriksson N,
Macdonald-Dunlop E,
Hedman ÅK,
Kalnapenkis A,
Enroth S,
Cozzetto D,
Digby-Bell J,
Marten J,
Folkersen L,
Herder C
and 29 more — show all
Jonsson L,
Bergen SE,
Gieger C,
Needham EJ,
Surendran P,
Paul DS,
Polasek O,
Thorand B,
Grallert H,
Roden M,
Võsa U,
Esko T,
Hayward C,
Johansson Å,
Gyllensten U,
Powell N,
Hansson O,
Mattsson-Carlgren N,
Joshi PK,
Danesh J,
Padyukov L,
Klareskog L,
Landén M,
Wilson JF,
Siegbahn A,
Wallentin L,
Mälarstig A,
Butterworth AS,
Peters JE
Estonian Biobank Research Team
Nature immunology · 2023 · PMID 37563310 · open access
12 pages+
Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes
Miller FW,
Chen W,
O'Hanlon TP,
Cooper RG,
Vencovsky J,
Rider LG,
Danko K,
Wedderburn LR,
Lundberg IE,
Pachman LM,
Reed AM,
Ytterberg SR
and 13 more — show all
Padyukov L,
Selva-O'Callaghan A,
Radstake TR,
Isenberg DA,
Chinoy H,
Ollier WE,
Scheet P,
Peng B,
Lee A,
Byun J,
Lamb JA,
Gregersen PK,
Amos CI
Myositis Genetics Consortium
Genes and immunity · 2015 · PMID 26291516
9 pages
High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences
Rivera NV,
Ronninger M,
Shchetynsky K,
Franke A,
Nöthen MM,
Müller-Quernheim J,
Schreiber S,
Adrianto I,
Karakaya B,
van Moorsel CH,
Navratilova Z,
Kolek V
and 9 more — show all
American journal of respiratory and critical care medicine · 2016 · PMID 26651848
9 pages
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population
Okada Y,
Terao C,
Ikari K,
Kochi Y,
Ohmura K,
Suzuki A,
Kawaguchi T,
Stahl EA,
Kurreeman FA,
Nishida N,
Ohmiya H,
Myouzen K
and 39 more — show all
Takahashi M,
Sawada T,
Nishioka Y,
Yukioka M,
Matsubara T,
Wakitani S,
Teshima R,
Tohma S,
Takasugi K,
Shimada K,
Murasawa A,
Honjo S,
Matsuo K,
Tanaka H,
Tajima K,
Suzuki T,
Iwamoto T,
Kawamura Y,
Tanii H,
Okazaki Y,
Sasaki T,
Gregersen PK,
Padyukov L,
Worthington J,
Siminovitch KA,
Lathrop M,
Taniguchi A,
Takahashi A,
Tokunaga K,
Kubo M,
Nakamura Y,
Kamatani N,
Mimori T,
Plenge RM,
Yamanaka H,
Momohara S,
Yamada R,
Matsuda F,
Yamamoto K
Nature genetics · 2012 · PMID 22446963
7 pages
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
Yin X,
Low HQ,
Wang L,
Li Y,
Ellinghaus E,
Han J,
Estivill X,
Sun L,
Zuo X,
Shen C,
Zhu C,
Zhang A
and 27 more — show all
Sanchez F,
Padyukov L,
Catanese JJ,
Krueger GG,
Duffin KC,
Mucha S,
Weichenthal M,
Weidinger S,
Lieb W,
Foo JN,
Li Y,
Sim K,
Liany H,
Irwan I,
Teo Y,
Theng CT,
Gupta R,
Bowcock A,
De Jager PL,
Qureshi AA,
de Bakker PI,
Seielstad M,
Liao W,
Ståhle M,
Franke A,
Zhang X,
Liu J
Nature communications · 2015 · PMID 25903422 · open access
7 pages
Genome-wide meta-analysis reveals shared new <i>loci</i> in systemic seropositive rheumatic diseases
Acosta-Herrera M,
Kerick M,
González-Serna D,
Wijmenga C,
Franke A,
Gregersen PK,
Padyukov L,
Worthington J,
Vyse TJ,
Alarcón-Riquelme ME,
Mayes MD,
Martin J
Myositis Genetics Consortium · Scleroderma Genetics Consortium
Annals of the rheumatic diseases · 2019 · PMID 30573655
6 pages
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
McGovern DP,
Gardet A,
Törkvist L,
Goyette P,
Essers J,
Taylor KD,
Neale BM,
Ong RT,
Lagacé C,
Li C,
Green T,
Stevens CR
and 42 more — show all
Beauchamp C,
Fleshner PR,
Carlson M,
D'Amato M,
Halfvarson J,
Hibberd ML,
Lördal M,
Padyukov L,
Andriulli A,
Colombo E,
Latiano A,
Palmieri O,
Bernard EJ,
Deslandres C,
Hommes DW,
de Jong DJ,
Stokkers PC,
Weersma RK,
Sharma Y,
Silverberg MS,
Cho JH,
Wu J,
Roeder K,
Brant SR,
Schumm LP,
Duerr RH,
Dubinsky MC,
Glazer NL,
Haritunians T,
Ippoliti A,
Melmed GY,
Siscovick DS,
Vasiliauskas EA,
Targan SR,
Annese V,
Wijmenga C,
Pettersson S,
Rotter JI,
Xavier RJ,
Daly MJ,
Rioux JD,
Seielstad M
NIDDK IBD Genetics Consortium
Nature genetics · 2010 · PMID 20228799
4 pages
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
Eyre S,
Bowes J,
Diogo D,
Lee A,
Barton A,
Martin P,
Zhernakova A,
Stahl E,
Viatte S,
McAllister K,
Amos CI,
Padyukov L
and 32 more — show all
Toes RE,
Huizinga TW,
Wijmenga C,
Trynka G,
Franke L,
Westra HJ,
Alfredsson L,
Hu X,
Sandor C,
de Bakker PI,
Davila S,
Khor CC,
Heng KK,
Andrews R,
Edkins S,
Hunt SE,
Langford C,
Symmons D,
Concannon P,
Onengut-Gumuscu S,
Rich SS,
Deloukas P,
Gonzalez-Gay MA,
Rodriguez-Rodriguez L,
Ärlsetig L,
Martin J,
Rantapää-Dahlqvist S,
Plenge RM,
Raychaudhuri S,
Klareskog L,
Gregersen PK,
Worthington J
Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate · Wellcome Trust Case Control Consortium
Nature genetics · 2012 · PMID 23143596 · open access
4 pages
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
Gateva V,
Sandling JK,
Hom G,
Taylor KE,
Chung SA,
Sun X,
Ortmann W,
Kosoy R,
Ferreira RC,
Nordmark G,
Gunnarsson I,
Svenungsson E
and 24 more — show all
Padyukov L,
Sturfelt G,
Jönsen A,
Bengtsson AA,
Rantapää-Dahlqvist S,
Baechler EC,
Brown EE,
Alarcón GS,
Edberg JC,
Ramsey-Goldman R,
McGwin G Jr,
Reveille JD,
Vilá LM,
Kimberly RP,
Manzi S,
Petri MA,
Lee A,
Gregersen PK,
Seldin MF,
Rönnblom L,
Criswell LA,
Syvänen AC,
Behrens TW,
Graham RR
Nature genetics · 2009 · PMID 19838195
3 pages
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci
Kim K,
Bang SY,
Lee HS,
Cho SK,
Choi CB,
Sung YK,
Kim TH,
Jun JB,
Yoo DH,
Kang YM,
Kim SK,
Suh CH
and 30 more — show all
Shim SC,
Lee SS,
Lee J,
Chung WT,
Choe JY,
Shin HD,
Lee JY,
Han BG,
Nath SK,
Eyre S,
Bowes J,
Pappas DA,
Kremer JM,
Gonzalez-Gay MA,
Rodriguez-Rodriguez L,
Ärlestig L,
Okada Y,
Diogo D,
Liao KP,
Karlson EW,
Raychaudhuri S,
Rantapää-Dahlqvist S,
Martin J,
Klareskog L,
Padyukov L,
Gregersen PK,
Worthington J,
Greenberg JD,
Plenge RM,
Bae SC
Annals of the rheumatic diseases · 2015 · PMID 24532676
3 pages
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
López-Isac E,
Acosta-Herrera M,
Kerick M,
Assassi S,
Satpathy AT,
Granja J,
Mumbach MR,
Beretta L,
Simeón CP,
Carreira P,
Ortego-Centeno N,
Castellvi I
and 30 more — show all
Bossini-Castillo L,
Carmona FD,
Orozco G,
Hunzelmann N,
Distler JHW,
Franke A,
Lunardi C,
Moroncini G,
Gabrielli A,
de Vries-Bouwstra J,
Wijmenga C,
Koeleman BPC,
Nordin A,
Padyukov L,
Hoffmann-Vold AM,
Lie B,
Proudman S,
Stevens W,
Nikpour M,
Vyse T,
Herrick AL,
Worthington J,
Denton CP,
Allanore Y,
Brown MA,
Radstake TRDJ,
Fonseca C,
Chang HY,
Mayes MD,
Martin J
European Scleroderma Group† · Australian Scleroderma Interest Group (ASIG)
Nature communications · 2019 · PMID 31672989 · open access
3 pages
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Saevarsdottir S,
Stefansdottir L,
Sulem P,
Thorleifsson G,
Ferkingstad E,
Rutsdottir G,
Glintborg B,
Westerlind H,
Grondal G,
Loft IC,
Sorensen SB,
Lie BA
and 66 more — show all
Brink M,
Ärlestig L,
Arnthorsson AO,
Baecklund E,
Banasik K,
Bank S,
Bjorkman LI,
Ellingsen T,
Erikstrup C,
Frei O,
Gjertsson I,
Gudbjartsson DF,
Gudjonsson SA,
Halldorsson GH,
Hendricks O,
Hillert J,
Hogdall E,
Jacobsen S,
Jensen DV,
Jonsson H,
Kastbom A,
Kockum I,
Kristensen S,
Kristjansdottir H,
Larsen MH,
Linauskas A,
Hauge EM,
Loft AG,
Ludviksson BR,
Lund SH,
Markusson T,
Masson G,
Melsted P,
Moore KHS,
Munk H,
Nielsen KR,
Norddahl GL,
Oddsson A,
Olafsdottir TA,
Olason PI,
Olsson T,
Ostrowski SR,
Hørslev-Petersen K,
Rognvaldsson S,
Sanner H,
Silberberg GN,
Stefansson H,
Sørensen E,
Sørensen IJ,
Turesson C,
Bergman T,
Alfredsson L,
Kvien TK,
Brunak S,
Steinsson K,
Andersen V,
Andreassen OA,
Rantapää-Dahlqvist S,
Hetland ML,
Klareskog L,
Askling J,
Padyukov L,
Pedersen OB,
Thorsteinsdottir U,
Jonsdottir I,
Stefansson K
Members of the DBDS Genomic Consortium · Danish RA Genetics Working Group and 1 more consortia
Annals of the rheumatic diseases · 2022 · PMID 35470158 · open access
3 pages
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis
Plenge RM,
Cotsapas C,
Davies L,
Price AL,
de Bakker PI,
Maller J,
Pe'er I,
Burtt NP,
Blumenstiel B,
DeFelice M,
Parkin M,
Barry R
and 26 more — show all
Winslow W,
Healy C,
Graham RR,
Neale BM,
Izmailova E,
Roubenoff R,
Parker AN,
Glass R,
Karlson EW,
Maher N,
Hafler DA,
Lee DM,
Seldin MF,
Remmers EF,
Lee AT,
Padyukov L,
Alfredsson L,
Coblyn J,
Weinblatt ME,
Gabriel SB,
Purcell S,
Klareskog L,
Gregersen PK,
Shadick NA,
Daly MJ,
Altshuler D
Nature genetics · 2007 · PMID 17982456
2 pages
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
Stahl EA,
Raychaudhuri S,
Remmers EF,
Xie G,
Eyre S,
Thomson BP,
Li Y,
Kurreeman FA,
Zhernakova A,
Hinks A,
Guiducci C,
Chen R
and 56 more — show all
Alfredsson L,
Amos CI,
Ardlie KG,
Barton A,
Bowes J,
Brouwer E,
Burtt NP,
Catanese JJ,
Coblyn J,
Coenen MJ,
Costenbader KH,
Criswell LA,
Crusius JB,
Cui J,
de Bakker PI,
De Jager PL,
Ding B,
Emery P,
Flynn E,
Harrison P,
Hocking LJ,
Huizinga TW,
Kastner DL,
Ke X,
Lee AT,
Liu X,
Martin P,
Morgan AW,
Padyukov L,
Posthumus MD,
Radstake TR,
Reid DM,
Seielstad M,
Seldin MF,
Shadick NA,
Steer S,
Tak PP,
Thomson W,
van der Helm-van Mil AH,
van der Horst-Bruinsma IE,
van der Schoot CE,
van Riel PL,
Weinblatt ME,
Wilson AG,
Wolbink GJ,
Wordsworth BP,
Wijmenga C,
Karlson EW,
Toes RE,
de Vries N,
Begovich AB,
Worthington J,
Siminovitch KA,
Gregersen PK,
Klareskog L,
Plenge RM
BIRAC Consortium · YEAR Consortium
Nature genetics · 2010 · PMID 20453842
2 pages
Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk
Fischer A,
Ellinghaus D,
Nutsua M,
Hofmann S,
Montgomery CG,
Iannuzzi MC,
Rybicki BA,
Petrek M,
Mrazek F,
Pabst S,
Grohé C,
Grunewald J
and 23 more — show all
Ronninger M,
Eklund A,
Padyukov L,
Mihailovic-Vucinic V,
Jovanovic D,
Sterclova M,
Homolka J,
Nöthen MM,
Herms S,
Gieger C,
Strauch K,
Winkelmann J,
Boehm BO,
Brand S,
Büning C,
Schürmann M,
Ellinghaus E,
Baurecht H,
Lieb W,
Nebel A,
Müller-Quernheim J,
Franke A,
Schreiber S
GenPhenReSa Consortium
American journal of respiratory and critical care medicine · 2015 · PMID 26051272
1 page
Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups
Rothwell S,
Cooper RG,
Lundberg IE,
Miller FW,
Gregersen PK,
Bowes J,
Vencovsky J,
Danko K,
Limaye V,
Selva-O'Callaghan A,
Hanna MG,
Machado PM
and 24 more — show all
Pachman LM,
Reed AM,
Rider LG,
Cobb J,
Platt H,
Molberg Ø,
Benveniste O,
Mathiesen P,
Radstake T,
Doria A,
De Bleecker J,
De Paepe B,
Maurer B,
Ollier WE,
Padyukov L,
O'Hanlon TP,
Lee A,
Amos CI,
Gieger C,
Meitinger T,
Winkelmann J,
Wedderburn LR,
Chinoy H,
Lamb JA
Myositis Genetics Consortium
Annals of the rheumatic diseases · 2016 · PMID 26362759
1 page
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