Sensitive
Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)
STK19 · rs389884
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome).
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) compared to the general population.
Source
High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences
Rivera NV,
Ronninger M,
Shchetynsky K,
Franke A,
Nöthen MM,
Müller-Quernheim J,
Schreiber S,
Adrianto I,
Karakaya B,
van Moorsel CH,
Navratilova Z,
Kolek V
and 9 more — show all
American journal of respiratory and critical care medicine · 2016 · PMID 26651848
Questions about rs389884
What is rs389884?
rs389884 is a single position in the genome, in or near the STK19 gene. Published research associates it with sarcoidosis (lofgren's syndrome vs non-lofgren's syndrome). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs389884 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs389884 come from?
GWAS Catalog, Am J Respir Crit Care Med 2016, PMID:26651848. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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