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Glial cell line-derived neurotrophic factor levels

GDNF-AS1 · rs62360376

What the study found

Who was studied 14,736 European ancestry individuals; replicated in 1,585 European or unknown ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.387 higher (95% confidence interval 0.35-0.43); p = 6 × 10−86.

How common The A allele had a frequency of about 91% in the people studied.

Where it sits Chromosome 5, band 5p13.2 — in an intron of GDNF-AS1.

What each result means

A/A Two copies of the version the research linked to Glial cell line-derived neurotrophic factor levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Glial cell line-derived neurotrophic factor levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Glial cell line-derived neurotrophic factor levels. This is the starting point the study compared everyone against.
Source

Questions about rs62360376

What is rs62360376?

rs62360376 is a single position in the genome, in or near the GDNF-AS1 gene. Published research associates it with glial cell line-derived neurotrophic factor levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs62360376 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs62360376 come from?

GWAS Catalog, Nature immunology 2023, PMID:37563310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Glial cell line-derived neurotrophic factor levels (rs62360376). MyGeneLog™. https://www.mygenelog.com/variants/rs62360376

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