Sensitive

Rheumatoid arthritis

TNFAIP3 · rs10499194

No connections yet. This position is published on its own. When a condition, drug or sense page here covers it, the links appear on this page automatically.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Rheumatoid arthritis compared to the general population. (GWAS Catalog, Nat Genet 2007, PMID:17982456)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Rheumatoid arthritis. (GWAS Catalog, Nat Genet 2007, PMID:17982456)
T/T Published research associates this genotype with typical/baseline likelihood of Rheumatoid arthritis — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2007, PMID:17982456)

Source: GWAS Catalog, Nat Genet 2007, PMID:17982456

Questions about rs10499194

What is rs10499194?

rs10499194 is a single position in the genome, in or near the TNFAIP3 gene. Published research associates it with rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10499194 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10499194 come from?

GWAS Catalog, Nat Genet 2007, PMID:17982456. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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