Sensitive

Rheumatoid arthritis

B3GNT2 · rs11900673

Where this position leads

Condition: Rheumatoid Arthritis

rs11900673 Condition: Rheumatoid Arthritis Rheumatoid Arthritis Condition rs11900673 rs11900673 B3GNT2

What the study found

Who was studied 4,074 Japanese ancestry cases, 16,891 Japanese ancestry controls; replicated in 5,277 Japanese ancestry cases, 21,684 Japanese ancestry controls.

The effect Each copy of the T allele carried 1.11 times the odds of Rheumatoid arthritis (95% confidence interval 1.07-1.15); p = 1 × 10−8.

How common The T allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 2, band 2p15 — between genes, 0.8 kb from B3GNT2.

What each result means

C/C No copy of the version the research linked to Rheumatoid arthritis. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Rheumatoid arthritis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Rheumatoid arthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11900673

What is rs11900673?

rs11900673 is a single position in the genome, in or near the B3GNT2 gene. Published research associates it with rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11900673 linked to?

On MyGeneLog this position is linked to Rheumatoid Arthritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs11900673 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11900673 come from?

GWAS Catalog, Nat Genet 2012, PMID:22446963. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Rheumatoid arthritis (rs11900673). MyGeneLog™. https://www.mygenelog.com/variants/rs11900673

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