Sensitive

Autoimmune thyroid disease

TBX21 · rs11079788

Where this position leads

Condition: Autoimmune Thyroid Disease

rs11079788 Condition: Autoimmune Thyroid Disease Autoimmune Thyroid Disease Condition rs11079788 rs11079788 TBX21

What the study found

Who was studied 30,234 European ancestry cases, 724,172 European ancestry controls.

The effect Each copy of the T allele carried 1.09 times the odds of Autoimmune thyroid disease; p = 3 × 10−15.

How common The T allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 17, band 17q21.32 — in an intron of TBX21.

What each result means

C/C No copy of the version the research linked to Autoimmune thyroid disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Autoimmune thyroid disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Autoimmune thyroid disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11079788

What is rs11079788?

rs11079788 is a single position in the genome, in or near the TBX21 gene. Published research associates it with autoimmune thyroid disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11079788 linked to?

On MyGeneLog this position is linked to Autoimmune Thyroid Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs11079788 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11079788 come from?

GWAS Catalog, Nature 2020, PMID:32581359. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Autoimmune thyroid disease (rs11079788). MyGeneLog™. https://www.mygenelog.com/variants/rs11079788

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