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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,556 European ancestry cases, 15,651 European ancestry controls.
The effect
Each copy of the G allele carried 2.74 times the odds of Idiopathic inflammatory myopathy (95% confidence interval 2.53–2.97); p = 9 × 10−133.
How common The G allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 11.9 kb from HLA-DRA.
What each result means
A/ANo copy of the version the research linked to Idiopathic inflammatory myopathy. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Idiopathic inflammatory myopathy. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Idiopathic inflammatory myopathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Annals of the rheumatic diseases · 2016 · PMID 26362759
Questions about rs3129843
What is rs3129843?
rs3129843 is a single position in the genome, in or near the HLA gene. Published research associates it with idiopathic inflammatory myopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3129843 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3129843 come from?
GWAS Catalog, Ann Rheum Dis 2015, PMID:26362759. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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