0 445246212220Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity4Meta AI6Microsoft · Copilot2Amazon1Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others20Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 4,074 Japanese ancestry cases, 16,891 Japanese ancestry controls; replicated in 5,277 Japanese ancestry cases, 21,684 Japanese ancestry controls.
The effect
Each copy of the C allele carried 1.14 times the odds of Rheumatoid arthritis (95% confidence interval 1.09-1.19); p = 2 × 10−8.
How common The C allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 6, band 6p23 — between genes, 2.2 kb from LOC105374939.
What each result means
C/CTwo copies of the version the research linked to Rheumatoid arthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Rheumatoid arthritis. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Rheumatoid arthritis. This is the starting point the study compared everyone against.
rs12529514 is a single position in the genome, in or near the CD83 gene. Published research associates it with rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12529514 linked to?
On MyGeneLog this position is linked to Rheumatoid Arthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs12529514 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12529514 come from?
GWAS Catalog, Nat Genet 2012, PMID:22446963. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 445246212220Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity4Meta AI6Microsoft · Copilot2Amazon1Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others20Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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