2 413214223222Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total41Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 4,074 Japanese ancestry cases, 16,891 Japanese ancestry controls; replicated in 5,277 Japanese ancestry cases, 21,684 Japanese ancestry controls.
The effect
Each copy of the T allele carried 1.12 times the odds of Rheumatoid arthritis (95% confidence interval 1.08-1.16); p = 6 × 10−10.
How common The T allele had a frequency of about 69% in the people studied.
Where it sits Chromosome 11, band 11q13.4 — in an intron of PDE2A.
What each result means
G/GNo copy of the version the research linked to Rheumatoid arthritis. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Rheumatoid arthritis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Rheumatoid arthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs3781913 is a single position in the genome, in or near the PDE2A gene. Published research associates it with rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3781913 linked to?
On MyGeneLog this position is linked to Rheumatoid Arthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs3781913 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3781913 come from?
GWAS Catalog, Nat Genet 2012, PMID:22446963. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 413214223222Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total41Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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