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Okada Y,
showing the first 20.
Subtype-specific gout susceptibility loci and enrichment of selection pressure on <i>ABCG2</i> and <i>ALDH2</i> identified by subtype genome-wide meta-analyses of clinically defined gout patients
Nakayama A,
Nakatochi M,
Kawamura Y,
Yamamoto K,
Nakaoka H,
Shimizu S,
Higashino T,
Koyama T,
Hishida A,
Kuriki K,
Watanabe M,
Shimizu T
and 42 more — show all
Ooyama K,
Ooyama H,
Nagase M,
Hidaka Y,
Matsui D,
Tamura T,
Nishiyama T,
Shimanoe C,
Katsuura-Kamano S,
Takashima N,
Shirai Y,
Kawaguchi M,
Takao M,
Sugiyama R,
Takada Y,
Nakamura T,
Nakashima H,
Tsunoda M,
Danjoh I,
Hozawa A,
Hosomichi K,
Toyoda Y,
Kubota Y,
Takada T,
Suzuki H,
Stiburkova B,
Major TJ,
Merriman TR,
Kuriyama N,
Mikami H,
Takezaki T,
Matsuo K,
Suzuki S,
Hosoya T,
Kamatani Y,
Kubo M,
Ichida K,
Wakai K,
Inoue I,
Okada Y,
Shinomiya N,
Matsuo H
Japan Gout Genomics Consortium (Japan Gout)
Annals of the rheumatic diseases · 2020 · PMID 32238385 · open access
6 pages
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci
Okada Y,
Kamatani Y,
Takahashi A,
Matsuda K,
Hosono N,
Ohmiya H,
Daigo Y,
Yamamoto K,
Kubo M,
Nakamura Y,
Kamatani N
Human molecular genetics · 2010 · PMID 20189936
5 pages
Identification of nine novel loci associated with white blood cell subtypes in a Japanese population
Okada Y,
Hirota T,
Kamatani Y,
Takahashi A,
Ohmiya H,
Kumasaka N,
Higasa K,
Yamaguchi-Kabata Y,
Hosono N,
Nalls MA,
Chen MH,
van Rooij FJ
and 19 more — show all
Smith AV,
Tanaka T,
Couper DJ,
Zakai NA,
Ferrucci L,
Longo DL,
Hernandez DG,
Witteman JC,
Harris TB,
O'Donnell CJ,
Ganesh SK,
Matsuda K,
Tsunoda T,
Tanaka T,
Kubo M,
Nakamura Y,
Tamari M,
Yamamoto K,
Kamatani N
PLoS genetics · 2011 · PMID 21738478 · open access
5 pages
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy
Liu H,
Irwanto A,
Fu X,
Yu G,
Yu Y,
Sun Y,
Wang C,
Wang Z,
Okada Y,
Low H,
Li Y,
Liany H
and 20 more — show all
Chen M,
Bao F,
Li J,
You J,
Zhang Q,
Liu J,
Chu T,
Andiappan AK,
Wang N,
Niu G,
Liu D,
Yu X,
Zhang L,
Tian H,
Zhou G,
Rotzschke O,
Chen S,
Zhang X,
Liu J,
Zhang F
Nature genetics · 2015 · PMID 25642632
5 pages
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis
van Rooij FJA,
Qayyum R,
Smith AV,
Zhou Y,
Trompet S,
Tanaka T,
Keller MF,
Chang LC,
Schmidt H,
Yang ML,
Chen MH,
Hayes J
and 88 more — show all
Johnson AD,
Yanek LR,
Mueller C,
Lange L,
Floyd JS,
Ghanbari M,
Zonderman AB,
Jukema JW,
Hofman A,
van Duijn CM,
Desch KC,
Saba Y,
Ozel AB,
Snively BM,
Wu JY,
Schmidt R,
Fornage M,
Klein RJ,
Fox CS,
Matsuda K,
Kamatani N,
Wild PS,
Stott DJ,
Ford I,
Slagboom PE,
Yang J,
Chu AY,
Lambert AJ,
Uitterlinden AG,
Franco OH,
Hofer E,
Ginsburg D,
Hu B,
Keating B,
Schick UM,
Brody JA,
Li JZ,
Chen Z,
Zeller T,
Guralnik JM,
Chasman DI,
Peters LL,
Kubo M,
Becker DM,
Li J,
Eiriksdottir G,
Rotter JI,
Levy D,
Grossmann V,
Patel KV,
Chen CH,
Ridker PM,
Tang H,
Launer LJ,
Rice KM,
Li-Gao R,
Ferrucci L,
Evans MK,
Choudhuri A,
Trompouki E,
Abraham BJ,
Yang S,
Takahashi A,
Kamatani Y,
Kooperberg C,
Harris TB,
Jee SH,
Coresh J,
Tsai FJ,
Longo DL,
Chen YT,
Felix JF,
Yang Q,
Psaty BM,
Boerwinkle E,
Becker LC,
Mook-Kanamori DO,
Wilson JG,
Gudnason V,
O'Donnell CJ,
Dehghan A,
Cupples LA,
Nalls MA,
Morris AP,
Okada Y,
Reiner AP,
Zon LI,
Ganesh SK
BioBank Japan Project
American journal of human genetics · 2017 · PMID 28017375
5 pages
Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data
Shungin D,
Haworth S,
Divaris K,
Agler CS,
Kamatani Y,
Keun Lee M,
Grinde K,
Hindy G,
Alaraudanjoki V,
Pesonen P,
Teumer A,
Holtfreter B
and 26 more — show all
Sakaue S,
Hirata J,
Yu YH,
Ridker PM,
Giulianini F,
Chasman DI,
Magnusson PKE,
Sudo T,
Okada Y,
Völker U,
Kocher T,
Anttonen V,
Laitala ML,
Orho-Melander M,
Sofer T,
Shaffer JR,
Vieira A,
Marazita ML,
Kubo M,
Furuichi Y,
North KE,
Offenbacher S,
Ingelsson E,
Franks PW,
Timpson NJ,
Johansson I
Nature communications · 2019 · PMID 31235808 · open access
5 pages
Stroke genetics informs drug discovery and risk prediction across ancestries
Mishra A,
Malik R,
Hachiya T,
Jürgenson T,
Namba S,
Posner DC,
Kamanu FK,
Koido M,
Le Grand Q,
Shi M,
He Y,
Georgakis MK
and 175 more — show all
Caro I,
Krebs K,
Liaw YC,
Vaura FC,
Lin K,
Winsvold BS,
Srinivasasainagendra V,
Parodi L,
Bae HJ,
Chauhan G,
Chong MR,
Tomppo L,
Akinyemi R,
Roshchupkin GV,
Habib N,
Jee YH,
Thomassen JQ,
Abedi V,
Cárcel-Márquez J,
Nygaard M,
Leonard HL,
Yang C,
Yonova-Doing E,
Knol MJ,
Lewis AJ,
Judy RL,
Ago T,
Amouyel P,
Armstrong ND,
Bakker MK,
Bartz TM,
Bennett DA,
Bis JC,
Bordes C,
Børte S,
Cain A,
Ridker PM,
Cho K,
Chen Z,
Cruchaga C,
Cole JW,
de Jager PL,
de Cid R,
Endres M,
Ferreira LE,
Geerlings MI,
Gasca NC,
Gudnason V,
Hata J,
He J,
Heath AK,
Ho YL,
Havulinna AS,
Hopewell JC,
Hyacinth HI,
Inouye M,
Jacob MA,
Jeon CE,
Jern C,
Kamouchi M,
Keene KL,
Kitazono T,
Kittner SJ,
Konuma T,
Kumar A,
Lacaze P,
Launer LJ,
Lee KJ,
Lepik K,
Li J,
Li L,
Manichaikul A,
Markus HS,
Marston NA,
Meitinger T,
Mitchell BD,
Montellano FA,
Morisaki T,
Mosley TH,
Nalls MA,
Nordestgaard BG,
O'Donnell MJ,
Okada Y,
Onland-Moret NC,
Ovbiagele B,
Peters A,
Psaty BM,
Rich SS,
Rosand J,
Sabatine MS,
Sacco RL,
Saleheen D,
Sandset EC,
Salomaa V,
Sargurupremraj M,
Sasaki M,
Satizabal CL,
Schmidt CO,
Shimizu A,
Smith NL,
Sloane KL,
Sutoh Y,
Sun YV,
Tanno K,
Tiedt S,
Tatlisumak T,
Torres-Aguila NP,
Tiwari HK,
Trégouët DA,
Trompet S,
Tuladhar AM,
Tybjærg-Hansen A,
van Vugt M,
Vibo R,
Verma SS,
Wiggins KL,
Wennberg P,
Woo D,
Wilson PWF,
Xu H,
Yang Q,
Yoon K,
Millwood IY,
Gieger C,
Ninomiya T,
Grabe HJ,
Jukema JW,
Rissanen IL,
Strbian D,
Kim YJ,
Chen PH,
Mayerhofer E,
Howson JMM,
Irvin MR,
Adams H,
Wassertheil-Smoller S,
Christensen K,
Ikram MA,
Rundek T,
Worrall BB,
Lathrop GM,
Riaz M,
Simonsick EM,
Kõrv J,
França PHC,
Zand R,
Prasad K,
Frikke-Schmidt R,
de Leeuw FE,
Liman T,
Haeusler KG,
Ruigrok YM,
Heuschmann PU,
Longstreth WT,
Jung KJ,
Bastarache L,
Paré G,
Damrauer SM,
Chasman DI,
Rotter JI,
Anderson CD,
Zwart JA,
Niiranen TJ,
Fornage M,
Liaw YP,
Seshadri S,
Fernández-Cadenas I,
Walters RG,
Ruff CT,
Owolabi MO,
Huffman JE,
Milani L,
Kamatani Y,
Dichgans M,
Debette S
COMPASS Consortium · INVENT Consortium and 13 more consortia
Nature · 2022 · PMID 36180795 · open access
5 pages
Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians
Chen P,
Takeuchi F,
Lee JY,
Li H,
Wu JY,
Liang J,
Long J,
Tabara Y,
Goodarzi MO,
Pereira MA,
Kim YJ,
Go MJ
and 59 more — show all
Stram DO,
Vithana E,
Khor CC,
Liu J,
Liao J,
Ye X,
Wang Y,
Lu L,
Young TL,
Lee J,
Thai AC,
Cheng CY,
van Dam RM,
Friedlander Y,
Heng CK,
Koh WP,
Chen CH,
Chang LC,
Pan WH,
Qi Q,
Isono M,
Zheng W,
Zheng W,
Cai Q,
Gao Y,
Yamamoto K,
Ohnaka K,
Takayanagi R,
Kita Y,
Ueshima H,
Hsiung CA,
Cui J,
Sheu WH,
Rotter JI,
Chen YD,
Hsu C,
Okada Y,
Kubo M,
Takahashi A,
Tanaka T,
van Rooij FJ,
Ganesh SK,
Huang J,
Huang T,
Yuan J,
Hwang JY,
Gross MD,
Assimes TL,
Miki T,
Shu XO,
Qi L,
Chen YT,
Lin X,
Aung T,
Wong TY,
Teo YY,
Kim BJ,
Kato N,
Tai ES
CHARGE Hematology Working Group
Diabetes · 2014 · PMID 24647736 · open access
4 pages
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index
Wen W,
Zheng W,
Zheng W,
Okada Y,
Takeuchi F,
Tabara Y,
Hwang JY,
Dorajoo R,
Li H,
Tsai FJ,
Yang X,
He J
and 98 more — show all
Wu Y,
He M,
Zhang Y,
Liang J,
Guo X,
Sheu WH,
Delahanty R,
Guo X,
Kubo M,
Yamamoto K,
Ohkubo T,
Go MJ,
Liu JJ,
Gan W,
Chen CC,
Gao Y,
Li S,
Lee NR,
Wu C,
Zhou X,
Song H,
Yao J,
Lee IT,
Long J,
Tsunoda T,
Akiyama K,
Takashima N,
Cho YS,
Ong RT,
Lu L,
Chen CH,
Tan A,
Rice TK,
Adair LS,
Gui L,
Allison M,
Lee WJ,
Cai Q,
Isomura M,
Umemura S,
Kim YJ,
Seielstad M,
Hixson J,
Xiang YB,
Isono M,
Kim BJ,
Sim X,
Lu W,
Nabika T,
Lee J,
Lim WY,
Gao YT,
Takayanagi R,
Kang DH,
Wong TY,
Hsiung CA,
Wu IC,
Juang JM,
Shi J,
Choi BY,
Aung T,
Hu F,
Kim MK,
Lim WY,
Wang TD,
Shin MH,
Lee J,
Ji BT,
Lee YH,
Young TL,
Shin DH,
Chun BY,
Cho MC,
Han BG,
Hwu CM,
Assimes TL,
Absher D,
Yan X,
Kim E,
Kuo JZ,
Kwon S,
Taylor KD,
Chen YD,
Rotter JI,
Qi L,
Zhu D,
Wu T,
Mohlke KL,
Gu D,
Mo Z,
Wu JY,
Lin X,
Miki T,
Tai ES,
Lee JY,
Kato N,
Shu XO,
Tanaka T
Human molecular genetics · 2014 · PMID 24861553
4 pages
Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals
Nakatochi M,
Kanai M,
Nakayama A,
Hishida A,
Kawamura Y,
Ichihara S,
Akiyama M,
Ikezaki H,
Furusyo N,
Shimizu S,
Yamamoto K,
Hirata M
and 38 more — show all
Okada R,
Kawai S,
Kawaguchi M,
Nishida Y,
Shimanoe C,
Ibusuki R,
Takezaki T,
Nakajima M,
Takao M,
Ozaki E,
Matsui D,
Nishiyama T,
Suzuki S,
Takashima N,
Kita Y,
Endoh K,
Kuriki K,
Uemura H,
Arisawa K,
Oze I,
Matsuo K,
Nakamura Y,
Mikami H,
Tamura T,
Nakashima H,
Nakamura T,
Kato N,
Matsuda K,
Murakami Y,
Matsubara T,
Naito M,
Kubo M,
Kamatani Y,
Shinomiya N,
Yokota M,
Wakai K,
Okada Y,
Matsuo H
Communications biology · 2019 · PMID 30993211 · open access
4 pages
Multiple loci are associated with white blood cell phenotypes
Nalls MA,
Couper DJ,
Tanaka T,
van Rooij FJ,
Chen MH,
Smith AV,
Toniolo D,
Zakai NA,
Yang Q,
Greinacher A,
Wood AR,
Garcia M
and 81 more — show all
Gasparini P,
Liu Y,
Lumley T,
Folsom AR,
Reiner AP,
Gieger C,
Lagou V,
Felix JF,
Völzke H,
Gouskova NA,
Biffi A,
Döring A,
Völker U,
Chong S,
Wiggins KL,
Rendon A,
Dehghan A,
Moore M,
Taylor K,
Wilson JG,
Lettre G,
Hofman A,
Bis JC,
Pirastu N,
Fox CS,
Meisinger C,
Sambrook J,
Arepalli S,
Nauck M,
Prokisch H,
Stephens J,
Glazer NL,
Cupples LA,
Okada Y,
Takahashi A,
Kamatani Y,
Matsuda K,
Tsunoda T,
Tanaka T,
Kubo M,
Nakamura Y,
Yamamoto K,
Kamatani N,
Stumvoll M,
Tönjes A,
Prokopenko I,
Illig T,
Patel KV,
Garner SF,
Kuhnel B,
Mangino M,
Oostra BA,
Thein SL,
Coresh J,
Wichmann HE,
Menzel S,
Lin J,
Pistis G,
Uitterlinden AG,
Spector TD,
Teumer A,
Eiriksdottir G,
Gudnason V,
Bandinelli S,
Frayling TM,
Chakravarti A,
van Duijn CM,
Melzer D,
Ouwehand WH,
Levy D,
Boerwinkle E,
Singleton AB,
Hernandez DG,
Longo DL,
Soranzo N,
Witteman JC,
Psaty BM,
Ferrucci L,
Harris TB,
O'Donnell CJ,
Ganesh SK
PLoS genetics · 2011 · PMID 21738480 · open access
3 pages
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits
Kim YJ,
Go MJ,
Hu C,
Hong CB,
Kim YK,
Lee JY,
Hwang JY,
Oh JH,
Kim DJ,
Kim NH,
Kim S,
Hong EJ
and 21 more — show all
Kim JH,
Min H,
Kim Y,
Zhang R,
Jia W,
Okada Y,
Takahashi A,
Kubo M,
Tanaka T,
Kamatani N,
Matsuda K,
Park T,
Oh B,
Kimm K,
Kang D,
Shin C,
Cho NH,
Kim HL,
Han BG,
Lee JY,
Cho YS
MAGIC consortium
Nature genetics · 2011 · PMID 21909109
3 pages
Discovery and fine mapping of serum protein loci through transethnic meta-analysis
Franceschini N,
van Rooij FJ,
Prins BP,
Feitosa MF,
Karakas M,
Eckfeldt JH,
Folsom AR,
Kopp J,
Vaez A,
Andrews JS,
Baumert J,
Boraska V
and 89 more — show all
Broer L,
Hayward C,
Ngwa JS,
Okada Y,
Polasek O,
Westra HJ,
Wang YA,
Del Greco M F,
Glazer NL,
Kapur K,
Kema IP,
Lopez LM,
Schillert A,
Smith AV,
Winkler CA,
Zgaga L,
Bandinelli S,
Bergmann S,
Boban M,
Bochud M,
Chen YD,
Davies G,
Dehghan A,
Ding J,
Doering A,
Durda JP,
Ferrucci L,
Franco OH,
Franke L,
Gunjaca G,
Hofman A,
Hsu FC,
Kolcic I,
Kraja A,
Kubo M,
Lackner KJ,
Launer L,
Loehr LR,
Li G,
Meisinger C,
Nakamura Y,
Schwienbacher C,
Starr JM,
Takahashi A,
Torlak V,
Uitterlinden AG,
Vitart V,
Waldenberger M,
Wild PS,
Kirin M,
Zeller T,
Zemunik T,
Zhang Q,
Ziegler A,
Blankenberg S,
Boerwinkle E,
Borecki IB,
Campbell H,
Deary IJ,
Frayling TM,
Gieger C,
Harris TB,
Hicks AA,
Koenig W,
O' Donnell CJ,
Fox CS,
Pramstaller PP,
Psaty BM,
Reiner AP,
Rotter JI,
Rudan I,
Snieder H,
Tanaka T,
van Duijn CM,
Vollenweider P,
Waeber G,
Wilson JF,
Witteman JC,
Wolffenbuttel BH,
Wright AF,
Wu Q,
Liu Y,
Jenny NS,
North KE,
Felix JF,
Alizadeh BZ,
Cupples LA,
Perry JR,
Morris AP
LifeLines Cohort Study
American journal of human genetics · 2012 · PMID 23022100
3 pages
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
Köttgen A,
Albrecht E,
Teumer A,
Vitart V,
Krumsiek J,
Hundertmark C,
Pistis G,
Ruggiero D,
O'Seaghdha CM,
Haller T,
Yang Q,
Tanaka T
and 214 more — show all
Johnson AD,
Kutalik Z,
Smith AV,
Shi J,
Struchalin M,
Middelberg RP,
Brown MJ,
Gaffo AL,
Pirastu N,
Li G,
Hayward C,
Zemunik T,
Huffman J,
Yengo L,
Zhao JH,
Demirkan A,
Feitosa MF,
Liu X,
Malerba G,
Lopez LM,
van der Harst P,
Li X,
Kleber ME,
Hicks AA,
Nolte IM,
Johansson A,
Murgia F,
Wild SH,
Bakker SJ,
Peden JF,
Dehghan A,
Steri M,
Tenesa A,
Lagou V,
Salo P,
Mangino M,
Rose LM,
Lehtimäki T,
Woodward OM,
Okada Y,
Tin A,
Müller C,
Oldmeadow C,
Putku M,
Czamara D,
Kraft P,
Frogheri L,
Thun GA,
Grotevendt A,
Gislason GK,
Harris TB,
Launer LJ,
McArdle P,
Shuldiner AR,
Boerwinkle E,
Coresh J,
Schmidt H,
Schallert M,
Martin NG,
Montgomery GW,
Kubo M,
Nakamura Y,
Tanaka T,
Munroe PB,
Samani NJ,
Jacobs DR Jr,
Liu K,
D'Adamo P,
Ulivi S,
Rotter JI,
Psaty BM,
Vollenweider P,
Waeber G,
Campbell S,
Devuyst O,
Navarro P,
Kolcic I,
Hastie N,
Balkau B,
Froguel P,
Esko T,
Salumets A,
Khaw KT,
Langenberg C,
Wareham NJ,
Isaacs A,
Kraja A,
Zhang Q,
Wild PS,
Scott RJ,
Holliday EG,
Org E,
Org E,
Viigimaa M,
Bandinelli S,
Metter JE,
Lupo A,
Trabetti E,
Sorice R,
Döring A,
Lattka E,
Strauch K,
Theis F,
Waldenberger M,
Wichmann HE,
Davies G,
Gow AJ,
Bruinenberg M,
Stolk RP,
Kooner JS,
Zhang W,
Winkelmann BR,
Boehm BO,
Lucae S,
Penninx BW,
Smit JH,
Curhan G,
Mudgal P,
Plenge RM,
Portas L,
Persico I,
Kirin M,
Wilson JF,
Mateo Leach I,
van Gilst WH,
Goel A,
Ongen H,
Hofman A,
Rivadeneira F,
Uitterlinden AG,
Imboden M,
von Eckardstein A,
Cucca F,
Nagaraja R,
Piras MG,
Nauck M,
Schurmann C,
Budde K,
Ernst F,
Farrington SM,
Theodoratou E,
Prokopenko I,
Stumvoll M,
Jula A,
Perola M,
Salomaa V,
Shin SY,
Spector TD,
Sala C,
Ridker PM,
Kähönen M,
Viikari J,
Hengstenberg C,
Nelson CP,
Meschia JF,
Nalls MA,
Sharma P,
Singleton AB,
Kamatani N,
Zeller T,
Burnier M,
Attia J,
Laan M,
Klopp N,
Hillege HL,
Kloiber S,
Choi H,
Pirastu M,
Tore S,
Probst-Hensch NM,
Völzke H,
Gudnason V,
Parsa A,
Schmidt R,
Whitfield JB,
Fornage M,
Gasparini P,
Siscovick DS,
Polašek O,
Campbell H,
Rudan I,
Bouatia-Naji N,
Metspalu A,
Loos RJ,
van Duijn CM,
Borecki IB,
Ferrucci L,
Gambaro G,
Deary IJ,
Wolffenbuttel BH,
Chambers JC,
März W,
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LifeLines Cohort Study · CARDIoGRAM Consortium and 3 more consortia
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Okada Y,
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BioBank Japan Project · CHARGE Consortium
Human molecular genetics · 2013 · PMID 23446634
3 pages
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci
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Shim SC,
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Annals of the rheumatic diseases · 2015 · PMID 24532676
3 pages
Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma
Shiraishi K,
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Watanabe SI,
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Goto Y,
Nokihara H,
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Yoshida A,
Goto K,
Hishida T,
Tsuboi M,
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Miyagi Y,
Nakayama H,
Yokose T,
Tanaka K,
Nagashima T,
Ohtaki Y,
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GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes
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Asian Genetic Epidemiology Network (AGEN) Consortium
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Questions about this list
Why is my paper here? I never gave you permission.
Nothing of your paper is reproduced here. This page records that a MyGeneLog™ page
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Why are all the authors listed instead of "et al."?
Because a study that needed 622 people is a different kind of study from one that
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My name is misspelt, or the paper is wrong.
Tell us and it is fixed. Names come from the public record and initials are
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My paper is not here. Does that mean you rejected it?
No. This catalogue is assembled from what a small team could read, and it is
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to it, not because it was assessed and turned down.
Which pages rest on a paper?
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