Standard
Leprosy
DEC1 · rs10817758
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Leprosy — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Leprosy.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Leprosy compared to the general population.
Source
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy
Liu H,
Irwanto A,
Fu X,
Yu G,
Yu Y,
Sun Y,
Wang C,
Wang Z,
Okada Y,
Low H,
Li Y,
Liany H
and 20 more — show all
Chen M,
Bao F,
Li J,
You J,
Zhang Q,
Liu J,
Chu T,
Andiappan AK,
Wang N,
Niu G,
Liu D,
Yu X,
Zhang L,
Tian H,
Zhou G,
Rotzschke O,
Chen S,
Zhang X,
Liu J,
Zhang F
Nature genetics · 2015 · PMID 25642632
Questions about rs10817758
What is rs10817758?
rs10817758 is a single position in the genome, in or near the DEC1 gene. Published research associates it with leprosy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10817758 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10817758 come from?
GWAS Catalog, Nat Genet 2015, PMID:25642632. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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