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White blood cell types

ERG · rs7275212

Where this position leads

Condition: Blood Cell Counts

rs7275212 Condition: Blood Cell Counts Blood Cell Counts Condition rs7275212 rs7275212 ERG

What the study found

Who was studied 8,794 Japanese ancestry individuals; replicated in 5,998 Japanese ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.197 higher (95% confidence interval 0.16-0.24); p = 2 × 10−18.

How common The T allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 21, band 21q22.2 — in an intron of ERG.

What each result means

A/A No copy of the version the research linked to White blood cell types. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to White blood cell types. That is a smaller link than two copies.
T/T Two copies of the version the research linked to White blood cell types. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7275212

What is rs7275212?

rs7275212 is a single position in the genome, in or near the ERG gene. Published research associates it with white blood cell types. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7275212 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs7275212 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7275212 come from?

GWAS Catalog, PLoS genetics 2011, PMID:21738478. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

White blood cell types (rs7275212). MyGeneLog™. https://www.mygenelog.com/variants/rs7275212

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