Standard
Body mass index
MC4R · rs591166
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index compared to the general population.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index.
T/T
Published research associates this genotype with typical/baseline likelihood of Body mass index — no copies of the reported risk allele.
Source
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index
Wen W,
Zheng W,
Zheng W,
Okada Y,
Takeuchi F,
Tabara Y,
Hwang JY,
Dorajoo R,
Li H,
Tsai FJ,
Yang X,
He J
and 98 more — show all
Wu Y,
He M,
Zhang Y,
Liang J,
Guo X,
Sheu WH,
Delahanty R,
Guo X,
Kubo M,
Yamamoto K,
Ohkubo T,
Go MJ,
Liu JJ,
Gan W,
Chen CC,
Gao Y,
Li S,
Lee NR,
Wu C,
Zhou X,
Song H,
Yao J,
Lee IT,
Long J,
Tsunoda T,
Akiyama K,
Takashima N,
Cho YS,
Ong RT,
Lu L,
Chen CH,
Tan A,
Rice TK,
Adair LS,
Gui L,
Allison M,
Lee WJ,
Cai Q,
Isomura M,
Umemura S,
Kim YJ,
Seielstad M,
Hixson J,
Xiang YB,
Isono M,
Kim BJ,
Sim X,
Lu W,
Nabika T,
Lee J,
Lim WY,
Gao YT,
Takayanagi R,
Kang DH,
Wong TY,
Hsiung CA,
Wu IC,
Juang JM,
Shi J,
Choi BY,
Aung T,
Hu F,
Kim MK,
Lim WY,
Wang TD,
Shin MH,
Lee J,
Ji BT,
Lee YH,
Young TL,
Shin DH,
Chun BY,
Cho MC,
Han BG,
Hwu CM,
Assimes TL,
Absher D,
Yan X,
Kim E,
Kuo JZ,
Kwon S,
Taylor KD,
Chen YD,
Rotter JI,
Qi L,
Zhu D,
Wu T,
Mohlke KL,
Gu D,
Mo Z,
Wu JY,
Lin X,
Miki T,
Tai ES,
Lee JY,
Kato N,
Shu XO,
Tanaka T
Human molecular genetics · 2014 · PMID 24861553
Questions about rs591166
What is rs591166?
rs591166 is a single position in the genome, in or near the MC4R gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs591166 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs591166 come from?
GWAS Catalog, Hum Mol Genet 2014, PMID:24861553. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants