0 443215123225Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI5Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 945 Japanese ancestry cases, 1,213 Japanese ancestry controls; replicated in 1,396 Japanese ancestry cases, 1,268 Japanese ancestry controls, 1,319 European ancestry cases, 514 European ancestry controls, 971 Polynesian ancestry cases, 565 Polynesian ancestry controls.
The effect
Each copy of the G allele carried 1.40 times the odds of Gout (95% confidence interval 1.25-1.57); p = 2 × 10−8.
How common The G allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 6, band 6p22.2 — between genes, 0.9 kb from H4C5.
What each result means
G/GTwo copies of the version the research linked to Gout. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Gout. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Gout. This is the starting point the study compared everyone against.
Annals of the rheumatic diseases · 2017 · PMID 27899376 · open access
Questions about rs11758351
What is rs11758351?
rs11758351 is a single position in the genome, in or near the HIST1H2BF gene. Published research associates it with gout. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11758351 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs11758351 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11758351 come from?
GWAS Catalog, Ann Rheum Dis 2016, PMID:27899376. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 443215123225Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI5Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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