G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gout compared to the general population. (GWAS Catalog, Ann Rheum Dis 2016, PMID:27899376)
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gout. (GWAS Catalog, Ann Rheum Dis 2016, PMID:27899376)
T/TPublished research associates this genotype with typical/baseline likelihood of Gout — no copies of the reported risk allele. (GWAS Catalog, Ann Rheum Dis 2016, PMID:27899376)
Source: GWAS Catalog, Ann Rheum Dis 2016, PMID:27899376
Questions about rs11758351
What is rs11758351?
rs11758351 is a single position in the genome, in or near the HIST1H2BF gene. Published research associates it with gout. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11758351 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs11758351 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11758351 come from?
GWAS Catalog, Ann Rheum Dis 2016, PMID:27899376. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.