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Gout (combined type)

NAA25 · rs116873087

Where this position leads

Condition: Gout

rs116873087 Condition: Gout Gout Condition rs116873087 rs116873087 NAA25

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Gout (combined type) — no copies of the reported risk allele.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gout (combined type).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gout (combined type) compared to the general population.
Source
Subtype-specific gout susceptibility loci and enrichment of selection pressure on <i>ABCG2</i> and <i>ALDH2</i> identified by subtype genome-wide meta-analyses of clinically defined gout patients
Nakayama A, Nakatochi M, Kawamura Y, Yamamoto K, Nakaoka H, Shimizu S, Higashino T, Koyama T, Hishida A, Kuriki K, Watanabe M, Shimizu T
and 42 more — show all
Ooyama K, Ooyama H, Nagase M, Hidaka Y, Matsui D, Tamura T, Nishiyama T, Shimanoe C, Katsuura-Kamano S, Takashima N, Shirai Y, Kawaguchi M, Takao M, Sugiyama R, Takada Y, Nakamura T, Nakashima H, Tsunoda M, Danjoh I, Hozawa A, Hosomichi K, Toyoda Y, Kubota Y, Takada T, Suzuki H, Stiburkova B, Major TJ, Merriman TR, Kuriyama N, Mikami H, Takezaki T, Matsuo K, Suzuki S, Hosoya T, Kamatani Y, Kubo M, Ichida K, Wakai K, Inoue I, Okada Y, Shinomiya N, Matsuo H
Japan Gout Genomics Consortium (Japan Gout)
Annals of the rheumatic diseases · 2020 · PMID 32238385 · open access

Questions about rs116873087

What is rs116873087?

rs116873087 is a single position in the genome, in or near the NAA25 gene. Published research associates it with gout (combined type). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs116873087 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs116873087 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116873087 come from?

GWAS Catalog, Ann Rheum Dis 2020, PMID:32238385. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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