Sensitive
EGFR mutation-positive lung adenocarcinoma
BPTF · rs7216064
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of EGFR mutation-positive lung adenocarcinoma compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with EGFR mutation-positive lung adenocarcinoma.
G/G
Published research associates this genotype with typical/baseline likelihood of EGFR mutation-positive lung adenocarcinoma — no copies of the reported risk allele.
Source
Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma
Shiraishi K,
Okada Y,
Takahashi A,
Kamatani Y,
Momozawa Y,
Ashikawa K,
Kunitoh H,
Matsumoto S,
Takano A,
Shimizu K,
Goto A,
Tsuta K
and 34 more — show all
Watanabe SI,
Ohe Y,
Watanabe Y,
Goto Y,
Nokihara H,
Furuta K,
Yoshida A,
Goto K,
Hishida T,
Tsuboi M,
Tsuchihara K,
Miyagi Y,
Nakayama H,
Yokose T,
Tanaka K,
Nagashima T,
Ohtaki Y,
Maeda D,
Imai K,
Minamiya Y,
Sakamoto H,
Saito A,
Shimada Y,
Sunami K,
Saito M,
Inazawa J,
Nakamura Y,
Yoshida T,
Yokota J,
Matsuda F,
Matsuo K,
Daigo Y,
Kubo M,
Kohno T
Nature communications · 2016 · PMID 27501781 · open access
Questions about rs7216064
What is rs7216064?
rs7216064 is a single position in the genome, in or near the BPTF gene. Published research associates it with egfr mutation-positive lung adenocarcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7216064 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7216064 come from?
GWAS Catalog, Nat Commun 2016, PMID:27501781. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants