Standard

HDL cholesterol

near BUD13 · rs11216126

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs11216126 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs11216126 rs11216126 near BUD13

What the study found

Who was studied 12,545 Korean ancestry individuals; replicated in Up to 30,395 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0322 mg/dL higher (95% confidence interval 0.027-0.037); p = 3 × 10−34.

How common The C allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 11, band 11q23.3 — between genes, 1.6 kb from BUD13.

What each result means

A/A No copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
C/C Two copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11216126

What is rs11216126?

rs11216126 is a single position in the genome, in or near the near BUD13 gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11216126 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs11216126 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11216126 come from?

GWAS Catalog, Nat Genet 2011, PMID:21909109. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol (rs11216126). MyGeneLog™. https://www.mygenelog.com/variants/rs11216126

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