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Serum uric acid levels

LRP2 · rs16856823

What the study found

Who was studied 121,745 Japanese ancestry individuals; replicated in at least 101,293 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.039 lower (95% confidence interval 0.029-0.049); p = 7 × 10−14.

How common The A allele had a frequency of about 81% in the people studied.

Where it sits Chromosome 2, band 2q31.1 — in an intron of LRP2.

What each result means

A/A Two copies of the version the research linked to Serum uric acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Serum uric acid levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum uric acid levels. This is the starting point the study compared everyone against.
Source

Questions about rs16856823

What is rs16856823?

rs16856823 is a single position in the genome, in or near the LRP2 gene. Published research associates it with serum uric acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs16856823 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16856823 come from?

GWAS Catalog, Communications biology 2019, PMID:30993211. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum uric acid levels (rs16856823). MyGeneLog™. https://www.mygenelog.com/variants/rs16856823

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