Number of decayed, missing and filled tooth surfaces or use of dentures
SYT14 · rs2046850
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,976 European ancestry individuals with decayed, missing or filled tooth surface measurement, 11,816 Hispanic/Latino individuals with decayed, missing or filled tooth surface measurement, 77,714 European ancestry dentures cases, 383,317 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.019 lower (95% confidence interval 0.013-0.025); p = 2 × 10−8.
How common The T allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 1, band 1q32.2 — in an intron of SYT14.
What each result means
C/CNo copy of the version the research linked to Number of decayed, missing and filled tooth surfaces or use of dentures. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Number of decayed, missing and filled tooth surfaces or use of dentures. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Number of decayed, missing and filled tooth surfaces or use of dentures. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 31235808 · open access
Questions about rs2046850
What is rs2046850?
rs2046850 is a single position in the genome, in or near the SYT14 gene. Published research associates it with number of decayed, missing and filled tooth surfaces or use of dentures. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2046850 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2046850 come from?
GWAS Catalog, Nature communications 2019, PMID:31235808. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Number of decayed, missing and filled tooth surfaces or use of dentures (rs2046850). MyGeneLog™. https://www.mygenelog.com/variants/rs2046850