C/CPublished research associates this genotype with typical/baseline likelihood of Renal underexcretion gout — no copies of the reported risk allele. (GWAS Catalog, Ann Rheum Dis 2020, PMID:32238385)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Renal underexcretion gout. (GWAS Catalog, Ann Rheum Dis 2020, PMID:32238385)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Renal underexcretion gout compared to the general population. (GWAS Catalog, Ann Rheum Dis 2020, PMID:32238385)
Source: GWAS Catalog, Ann Rheum Dis 2020, PMID:32238385
Questions about rs76741582
What is rs76741582?
rs76741582 is a single position in the genome, in or near the SLC22A11 gene. Published research associates it with renal underexcretion gout. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76741582 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs76741582 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76741582 come from?
GWAS Catalog, Ann Rheum Dis 2020, PMID:32238385. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.