NEO1 · rs6495046
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,976 European ancestry individuals with decayed, missing or filled tooth surface measurement, 11,816 Hispanic/Latino individuals with decayed, missing or filled tooth surface measurement, 77,714 European ancestry dentures cases, 383,317 European ancestry controls.
The effect Each copy of the C allele shifted the measure 0.017 lower (95% confidence interval 0.012-0.022); p = 3 × 10−10.
How common The C allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 15, band 15q24.1 — in an intron of NEO1.
rs6495046 is a single position in the genome, in or near the NEO1 gene. Published research associates it with number of decayed, missing and filled tooth surfaces or use of dentures. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2019, PMID:31235808. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Number of decayed, missing and filled tooth surfaces or use of dentures (rs6495046). MyGeneLog™. https://www.mygenelog.com/variants/rs6495046