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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 77,714 European ancestry cases, 383,317 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.051 lower (95% confidence interval 0.036-0.066); p = 8 × 10−11.
How common The A allele had a frequency of about 89% in the people studied.
Where it sits Chromosome 9, band 9q21.2 — in an intron of PCA3.
What each result means
A/ATwo copies of the version the research linked to Dentures. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Dentures. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Dentures. This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 31235808 · open access
Questions about rs7852129
What is rs7852129?
rs7852129 is a single position in the genome, in or near the PRUNE2 gene. Published research associates it with dentures. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7852129 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7852129 come from?
GWAS Catalog, Nature communications 2019, PMID:31235808. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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