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19 matches for
Zhernakova A.
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Okada Y,
Wu D,
Trynka G,
Raj T,
Terao C,
Ikari K,
Kochi Y,
Ohmura K,
Suzuki A,
Yoshida S,
Graham RR,
Manoharan A
and 83 more — show all
Ortmann W,
Bhangale T,
Denny JC,
Carroll RJ,
Eyler AE,
Greenberg JD,
Kremer JM,
Pappas DA,
Jiang L,
Yin J,
Ye L,
Su DF,
Yang J,
Xie G,
Keystone E,
Westra HJ,
Esko T,
Metspalu A,
Zhou X,
Gupta N,
Mirel D,
Stahl EA,
Diogo D,
Cui J,
Liao K,
Guo MH,
Myouzen K,
Kawaguchi T,
Coenen MJ,
van Riel PL,
van de Laar MA,
Guchelaar HJ,
Huizinga TW,
Dieudé P,
Mariette X,
Bridges SL Jr,
Zhernakova A,
Toes RE,
Tak PP,
Miceli-Richard C,
Bang SY,
Lee HS,
Martin J,
Gonzalez-Gay MA,
Rodriguez-Rodriguez L,
Rantapää-Dahlqvist S,
Arlestig L,
Choi HK,
Kamatani Y,
Galan P,
Lathrop M,
Eyre S,
Bowes J,
Barton A,
de Vries N,
Moreland LW,
Criswell LA,
Karlson EW,
Taniguchi A,
Yamada R,
Kubo M,
Liu JS,
Bae SC,
Worthington J,
Padyukov L,
Klareskog L,
Gregersen PK,
Raychaudhuri S,
Stranger BE,
De Jager PL,
Franke L,
Visscher PM,
Brown MA,
Yamanaka H,
Mimori T,
Takahashi A,
Xu H,
Behrens TW,
Siminovitch KA,
Momohara S,
Matsuda F,
Yamamoto K,
Plenge RM
RACI consortium · GARNET consortium
Nature · 2014 · PMID 24390342 · open access
12 pages+
The effect of host genetics on the gut microbiome
Bonder MJ,
Kurilshikov A,
Tigchelaar EF,
Mujagic Z,
Imhann F,
Vila AV,
Deelen P,
Vatanen T,
Schirmer M,
Smeekens SP,
Zhernakova DV,
Jankipersadsing SA
and 18 more — show all
Jaeger M,
Oosting M,
Cenit MC,
Masclee AA,
Swertz MA,
Li Y,
Kumar V,
Joosten L,
Harmsen H,
Weersma RK,
Franke L,
Hofker MH,
Xavier RJ,
Jonkers D,
Netea MG,
Wijmenga C,
Fu J,
Zhernakova A
Nature genetics · 2016 · PMID 27694959
12 pages+
Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations
Márquez A,
Kerick M,
Zhernakova A,
Gutierrez-Achury J,
Chen WM,
Onengut-Gumuscu S,
González-Álvaro I,
Rodriguez-Rodriguez L,
Rios-Fernández R,
González-Gay MA,
Mayes MD,
Raychaudhuri S
and 3 more — show all
Coeliac Disease Immunochip Consortium · Rheumatoid Arthritis Consortium International for Immunochip (RACI) and 2 more consortia
Genome medicine · 2018 · PMID 30572963 · open access
12 pages+
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
Folkersen L,
Gustafsson S,
Wang Q,
Hansen DH,
Hedman ÅK,
Schork A,
Page K,
Zhernakova DV,
Wu Y,
Peters J,
Eriksson N,
Bergen SE
and 71 more — show all
Boutin TS,
Bretherick AD,
Enroth S,
Kalnapenkis A,
Gådin JR,
Suur BE,
Chen Y,
Matic L,
Gale JD,
Lee J,
Zhang W,
Quazi A,
Ala-Korpela M,
Choi SH,
Claringbould A,
Danesh J,
Davey Smith G,
de Masi F,
Elmståhl S,
Engström G,
Fauman E,
Fernandez C,
Franke L,
Franks PW,
Giedraitis V,
Haley C,
Hamsten A,
Ingason A,
Johansson Å,
Joshi PK,
Lind L,
Lindgren CM,
Lubitz S,
Palmer T,
Macdonald-Dunlop E,
Magnusson M,
Melander O,
Michaelsson K,
Morris AP,
Mägi R,
Nagle MW,
Nilsson PM,
Nilsson J,
Orho-Melander M,
Polasek O,
Prins B,
Pålsson E,
Qi T,
Sjögren M,
Sundström J,
Surendran P,
Võsa U,
Werge T,
Wernersson R,
Westra HJ,
Yang J,
Zhernakova A,
Ärnlöv J,
Fu J,
Smith JG,
Esko T,
Hayward C,
Gyllensten U,
Landen M,
Siegbahn A,
Wilson JF,
Wallentin L,
Butterworth AS,
Holmes MV,
Ingelsson E,
Mälarstig A
Nature metabolism · 2020 · PMID 33067605
12 pages+
Genome-wide characterization of circulating metabolic biomarkers
Karjalainen MK,
Karthikeyan S,
Oliver-Williams C,
Sliz E,
Allara E,
Fung WT,
Surendran P,
Zhang W,
Jousilahti P,
Kristiansson K,
Salomaa V,
Goodwin M
and 75 more — show all
Hughes DA,
Boehnke M,
Fernandes Silva L,
Yin X,
Mahajan A,
Neville MJ,
van Zuydam NR,
de Mutsert R,
Li-Gao R,
Mook-Kanamori DO,
Demirkan A,
Liu J,
Noordam R,
Trompet S,
Chen Z,
Kartsonaki C,
Li L,
Lin K,
Hagenbeek FA,
Hottenga JJ,
Pool R,
Ikram MA,
van Meurs J,
Haller T,
Milaneschi Y,
Kähönen M,
Mishra PP,
Joshi PK,
Macdonald-Dunlop E,
Mangino M,
Zierer J,
Acar IE,
Hoyng CB,
Lechanteur YTE,
Franke L,
Kurilshikov A,
Zhernakova A,
Beekman M,
van den Akker EB,
Kolcic I,
Polasek O,
Rudan I,
Gieger C,
Waldenberger M,
Asselbergs FW,
Hayward C,
Fu J,
den Hollander AI,
Menni C,
Spector TD,
Wilson JF,
Lehtimäki T,
Raitakari OT,
Penninx BWJH,
Esko T,
Walters RG,
Jukema JW,
Sattar N,
Ghanbari M,
Willems van Dijk K,
Karpe F,
McCarthy MI,
Laakso M,
Järvelin MR,
Timpson NJ,
Perola M,
Kooner JS,
Chambers JC,
van Duijn C,
Slagboom PE,
Boomsma DI,
Danesh J,
Ala-Korpela M,
Butterworth AS,
Kettunen J
China Kadoorie Biobank Collaborative Group · Estonian Biobank Research Team and 1 more consortia
Nature · 2024 · PMID 38448586 · open access
12 pages+
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
Trynka G,
Hunt KA,
Bockett NA,
Romanos J,
Mistry V,
Szperl A,
Bakker SF,
Bardella MT,
Bhaw-Rosun L,
Castillejo G,
de la Concha EG,
de Almeida RC
and 52 more — show all
Dias KR,
van Diemen CC,
Dubois PC,
Duerr RH,
Edkins S,
Franke L,
Fransen K,
Gutierrez J,
Heap GA,
Hrdlickova B,
Hunt S,
Plaza Izurieta L,
Izzo V,
Joosten LA,
Langford C,
Mazzilli MC,
Mein CA,
Midah V,
Mitrovic M,
Mora B,
Morelli M,
Nutland S,
Núñez C,
Onengut-Gumuscu S,
Pearce K,
Platteel M,
Polanco I,
Potter S,
Ribes-Koninckx C,
Ricaño-Ponce I,
Rich SS,
Rybak A,
Santiago JL,
Senapati S,
Sood A,
Szajewska H,
Troncone R,
Varadé J,
Wallace C,
Wolters VM,
Zhernakova A,
Thelma BK,
Cukrowska B,
Urcelay E,
Bilbao JR,
Mearin ML,
Barisani D,
Barrett JC,
Plagnol V,
Deloukas P,
Wijmenga C,
van Heel DA
Spanish Consortium on the Genetics of Coeliac Disease (CEGEC) · PreventCD Study Group and 1 more consortia
Nature genetics · 2011 · PMID 22057235 · open access
7 pages
Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility
Díaz-Muñoz C,
Bozzarelli I,
Lopera-Maya EA,
Belbasis L,
Lo Faro V,
Camargo Tavares L,
Heredia-Fernández F,
Di Lorenzo B,
Sinha T,
Esteban Blanco C,
Favé MJ,
Awadalla P
and 5 more — show all
Gut · 2026 · PMID 41558814 · open access
6 pages
Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms
Di Lorenzo B,
Camargo Tavares L,
Díaz-Muñoz C,
Heredia-Fernández F,
Bozzarelli I,
Esteban Blanco C,
Wang Z,
Smit RAJ,
Loos RJF,
Hirbo J,
Cox NJ,
Straub P
and 57 more — show all
Favé MJ,
Awadalla P,
Pozdeyev N,
Gignoux CR,
Gudbjartsson DF,
Thorleifsson G,
Jonsdottir I,
Stefansson K,
Abner E,
Palta P,
Williams AT,
Coley K,
Sze G,
John C,
Richmond A,
McCartney D,
Hayward C,
Mulford AJ,
Sanders AR,
Peculis R,
Rovite V,
Dombrovska MS,
Capasso M,
Lo Faro V,
Sinha T,
Lopera Maya EA,
Zhernakova A,
Wang Y,
Martin A,
Vanderwerff B,
Zöllner S,
Ferolito BR,
Pereira AC,
Gaziano JM,
Cho K,
Caruth L,
Guare L,
Kripke CM,
Rader DJ,
Verma SS,
Verma A,
Saad C,
Mbarek H,
Chao PY,
Chen TT,
Lin YF,
Feng YA,
Challa PK,
Khalili H,
Andries A,
Ness-Jensen E,
Brumpton BM,
Grover M,
Lemmelä S,
Sanna S,
Bonfiglio F,
D'Amato M
Colorado Center for Personalized Medicine · Estonian Biobank Research Team and 3 more consortia
Gut · 2026 · PMID 42425734
6 pages
Large-scale association analyses identify host factors influencing human gut microbiome composition
Kurilshikov A,
Medina-Gomez C,
Bacigalupe R,
Radjabzadeh D,
Wang J,
Demirkan A,
Le Roy CI,
Raygoza Garay JA,
Finnicum CT,
Liu X,
Zhernakova DV,
Bonder MJ
and 92 more — show all
Hansen TH,
Frost F,
Rühlemann MC,
Turpin W,
Moon JY,
Kim HN,
Lüll K,
Barkan E,
Shah SA,
Fornage M,
Szopinska-Tokov J,
Wallen ZD,
Borisevich D,
Agreus L,
Andreasson A,
Bang C,
Bedrani L,
Bell JT,
Bisgaard H,
Boehnke M,
Boomsma DI,
Burk RD,
Claringbould A,
Croitoru K,
Davies GE,
van Duijn CM,
Duijts L,
Falony G,
Fu J,
van der Graaf A,
Hansen T,
Homuth G,
Hughes DA,
Ijzerman RG,
Jackson MA,
Jaddoe VWV,
Joossens M,
Jørgensen T,
Keszthelyi D,
Knight R,
Laakso M,
Laudes M,
Launer LJ,
Lieb W,
Lusis AJ,
Masclee AAM,
Moll HA,
Mujagic Z,
Qibin Q,
Rothschild D,
Shin H,
Sørensen SJ,
Steves CJ,
Thorsen J,
Timpson NJ,
Tito RY,
Vieira-Silva S,
Völker U,
Völzke H,
Võsa U,
Wade KH,
Walter S,
Watanabe K,
Weiss S,
Weiss FU,
Weissbrod O,
Westra HJ,
Willemsen G,
Payami H,
Jonkers DMAE,
Arias Vasquez A,
de Geus EJC,
Meyer KA,
Stokholm J,
Segal E,
Org E,
Wijmenga C,
Kim HL,
Kaplan RC,
Spector TD,
Uitterlinden AG,
Rivadeneira F,
Franke A,
Lerch MM,
Franke L,
Sanna S,
D'Amato M,
Pedersen O,
Paterson AD,
Kraaij R,
Raes J,
Zhernakova A
Nature genetics · 2021 · PMID 33462485
5 pages
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci
Zhernakova A,
Stahl EA,
Trynka G,
Raychaudhuri S,
Festen EA,
Franke L,
Westra HJ,
Fehrmann RS,
Kurreeman FA,
Thomson B,
Gupta N,
Romanos J
and 24 more — show all
McManus R,
Ryan AW,
Turner G,
Brouwer E,
Posthumus MD,
Remmers EF,
Tucci F,
Toes R,
Grandone E,
Mazzilli MC,
Rybak A,
Cukrowska B,
Coenen MJ,
Radstake TR,
van Riel PL,
Li Y,
de Bakker PI,
Gregersen PK,
Worthington J,
Siminovitch KA,
Klareskog L,
Huizinga TW,
Wijmenga C,
Plenge RM
PLoS genetics · 2011 · PMID 21383967 · open access
4 pages
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
Eyre S,
Bowes J,
Diogo D,
Lee A,
Barton A,
Martin P,
Zhernakova A,
Stahl E,
Viatte S,
McAllister K,
Amos CI,
Padyukov L
and 32 more — show all
Toes RE,
Huizinga TW,
Wijmenga C,
Trynka G,
Franke L,
Westra HJ,
Alfredsson L,
Hu X,
Sandor C,
de Bakker PI,
Davila S,
Khor CC,
Heng KK,
Andrews R,
Edkins S,
Hunt SE,
Langford C,
Symmons D,
Concannon P,
Onengut-Gumuscu S,
Rich SS,
Deloukas P,
Gonzalez-Gay MA,
Rodriguez-Rodriguez L,
Ärlsetig L,
Martin J,
Rantapää-Dahlqvist S,
Plenge RM,
Raychaudhuri S,
Klareskog L,
Gregersen PK,
Worthington J
Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate · Wellcome Trust Case Control Consortium
Nature genetics · 2012 · PMID 23143596 · open access
4 pages
Multiple common variants for celiac disease influencing immune gene expression
Dubois PC,
Trynka G,
Franke L,
Hunt KA,
Romanos J,
Curtotti A,
Zhernakova A,
Heap GA,
Adány R,
Aromaa A,
Bardella MT,
van den Berg LH
and 55 more — show all
Bockett NA,
de la Concha EG,
Dema B,
Fehrmann RS,
Fernández-Arquero M,
Fiatal S,
Grandone E,
Green PM,
Groen HJ,
Gwilliam R,
Houwen RH,
Hunt SE,
Kaukinen K,
Kelleher D,
Korponay-Szabo I,
Kurppa K,
MacMathuna P,
Mäki M,
Mazzilli MC,
McCann OT,
Mearin ML,
Mein CA,
Mirza MM,
Mistry V,
Mora B,
Morley KI,
Mulder CJ,
Murray JA,
Núñez C,
Oosterom E,
Ophoff RA,
Polanco I,
Peltonen L,
Platteel M,
Rybak A,
Salomaa V,
Schweizer JJ,
Sperandeo MP,
Tack GJ,
Turner G,
Veldink JH,
Verbeek WH,
Weersma RK,
Wolters VM,
Urcelay E,
Cukrowska B,
Greco L,
Neuhausen SL,
McManus R,
Barisani D,
Deloukas P,
Barrett JC,
Saavalainen P,
Wijmenga C,
van Heel DA
Nature genetics · 2010 · PMID 20190752 · open access
3 pages
Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease
Ricaño-Ponce I,
Gutierrez-Achury J,
Costa AF,
Deelen P,
Kurilshikov A,
Zorro MM,
Platteel M,
van der Graaf A,
Sanna S,
Daffra O,
Zhernakova A,
Fu J
and 6 more — show all
Consortium for the study of genetic associations of celiac disease in Latin-America
European journal of human genetics : EJHG · 2020 · PMID 31591516
3 pages
Newly identified genetic risk variants for celiac disease related to the immune response
Hunt KA,
Zhernakova A,
Turner G,
Heap GA,
Franke L,
Bruinenberg M,
Romanos J,
Dinesen LC,
Ryan AW,
Panesar D,
Gwilliam R,
Takeuchi F
and 25 more — show all
McLaren WM,
Holmes GK,
Howdle PD,
Walters JR,
Sanders DS,
Playford RJ,
Trynka G,
Mulder CJ,
Mearin ML,
Verbeek WH,
Trimble V,
Stevens FM,
O'Morain C,
Kennedy NP,
Kelleher D,
Pennington DJ,
Strachan DP,
McArdle WL,
Mein CA,
Wapenaar MC,
Deloukas P,
McGinnis R,
McManus R,
Wijmenga C,
van Heel DA
Nature genetics · 2008 · PMID 18311140
2 pages
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
Stahl EA,
Raychaudhuri S,
Remmers EF,
Xie G,
Eyre S,
Thomson BP,
Li Y,
Kurreeman FA,
Zhernakova A,
Hinks A,
Guiducci C,
Chen R
and 56 more — show all
Alfredsson L,
Amos CI,
Ardlie KG,
Barton A,
Bowes J,
Brouwer E,
Burtt NP,
Catanese JJ,
Coblyn J,
Coenen MJ,
Costenbader KH,
Criswell LA,
Crusius JB,
Cui J,
de Bakker PI,
De Jager PL,
Ding B,
Emery P,
Flynn E,
Harrison P,
Hocking LJ,
Huizinga TW,
Kastner DL,
Ke X,
Lee AT,
Liu X,
Martin P,
Morgan AW,
Padyukov L,
Posthumus MD,
Radstake TR,
Reid DM,
Seielstad M,
Seldin MF,
Shadick NA,
Steer S,
Tak PP,
Thomson W,
van der Helm-van Mil AH,
van der Horst-Bruinsma IE,
van der Schoot CE,
van Riel PL,
Weinblatt ME,
Wilson AG,
Wolbink GJ,
Wordsworth BP,
Wijmenga C,
Karlson EW,
Toes RE,
de Vries N,
Begovich AB,
Worthington J,
Siminovitch KA,
Gregersen PK,
Klareskog L,
Plenge RM
BIRAC Consortium · YEAR Consortium
Nature genetics · 2010 · PMID 20453842
2 pages
Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome
Bonfiglio F,
Zheng T,
Garcia-Etxebarria K,
Hadizadeh F,
Bujanda L,
Bresso F,
Agreus L,
Andreasson A,
Dlugosz A,
Lindberg G,
Schmidt PT,
Karling P
and 24 more — show all
Ohlsson B,
Simren M,
Walter S,
Nardone G,
Cuomo R,
Usai-Satta P,
Galeazzi F,
Neri M,
Portincasa P,
Bellini M,
Barbara G,
Latiano A,
Hübenthal M,
Thijs V,
Netea MG,
Jonkers D,
Chang L,
Mayer EA,
Wouters MM,
Boeckxstaens G,
Camilleri M,
Franke A,
Zhernakova A,
D'Amato M
Gastroenterology · 2018 · PMID 29626450
2 pages
Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project
Lopera-Maya EA,
Kurilshikov A,
van der Graaf A,
Hu S,
Andreu-Sánchez S,
Chen L,
Vila AV,
Gacesa R,
Sinha T,
Collij V,
Klaassen MAY,
Bolte LA
and 9 more — show all
LifeLines Cohort Study
Nature genetics · 2022 · PMID 35115690
2 pages
Genetic Association of a Gain-of-Function IFNGR1 Polymorphism and the Intergenic Region LNCAROD/DKK1 With Behçet's Disease
Ortiz Fernández L,
Coit P,
Yilmaz V,
Yentür SP,
Alibaz-Oner F,
Aksu K,
Erken E,
Düzgün N,
Keser G,
Cefle A,
Yazici A,
Ergen A
and 25 more — show all
Alpsoy E,
Salvarani C,
Casali B,
Kısacık B,
Kötter I,
Henes J,
Çınar M,
Schaefer A,
Nohutcu RM,
Zhernakova A,
Wijmenga C,
Takeuchi F,
Harihara S,
Kaburaki T,
Messedi M,
Song YW,
Kaşifoğlu T,
Carmona FD,
Guthridge JM,
James JA,
Martin J,
González Escribano MF,
Saruhan-Direskeneli G,
Direskeneli H,
Sawalha AH
Arthritis & rheumatology (Hoboken, N.J.) · 2021 · PMID 33393726
1 page
GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome
Bonfiglio F,
Liu X,
Smillie C,
Pandit A,
Kurilshikov A,
Bacigalupe R,
Zheng T,
Nim H,
Garcia-Etxebarria K,
Bujanda L,
Andreasson A,
Agreus L
and 15 more — show all
Walter S,
Abecasis G,
Eijsbouts C,
Jostins L,
Parkes M,
Hughes DA,
Timpson N,
Raes J,
Franke A,
Kennedy NA,
Regev A,
Zhernakova A,
Simren M,
Camilleri M,
D'Amato M
Cell genomics · 2021 · PMID 34957435 · open access
1 page
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