A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Celiac disease compared to the general population. (GWAS Catalog, Nat Genet 2010, PMID:20190752)
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Celiac disease. (GWAS Catalog, Nat Genet 2010, PMID:20190752)
C/CPublished research associates this genotype with typical/baseline likelihood of Celiac disease — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2010, PMID:20190752)
rs10806425 is a single position in the genome, in or near the MAP3K7 gene. Published research associates it with celiac disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10806425 linked to?
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs10806425 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10806425 come from?
GWAS Catalog, Nat Genet 2010, PMID:20190752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.