Sensitive

Celiac disease

TNFAIP3 · rs2327832

Where this position leads

Condition: Celiac Disease

rs2327832 Condition: Celiac Disease Celiac Disease Condition rs2327832 rs2327832 TNFAIP3

What the study found

Who was studied 4,533 European ancestry cases, 10,750 European ancestry controls; replicated in 4,918 European ancestry cases, 5,684 European ancestry controls.

The effect Each copy of the G allele carried 1.23 times the odds of Celiac disease (95% confidence interval 1.17-1.28); p = 4 × 10−19.

How common The G allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 6, band 6q23.3 — inside LINC03004.

What each result means

A/A No copy of the version the research linked to Celiac disease. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Celiac disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Celiac disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2327832

What is rs2327832?

rs2327832 is a single position in the genome, in or near the TNFAIP3 gene. Published research associates it with celiac disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2327832 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs2327832?

Subjects that appear in the title or abstract of the same papers as this rsID include gut and food intolerance (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2327832 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2327832 come from?

GWAS Catalog, Nat Genet 2010, PMID:20190752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Celiac disease (rs2327832). MyGeneLog™. https://www.mygenelog.com/variants/rs2327832

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