Standard

Stool frequency

near HMGA2 · rs56074694

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 167,966 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.018 higher (95% confidence interval 0.012-0.024); p = 7 × 10⁻¹⁰.

How common The A allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 12, band 12q14.3 — between genes, 11.5 kb from MIR6074.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Stool frequency compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Stool frequency.

G/G Published research associates this genotype with typical/baseline likelihood of Stool frequency — no copies of the reported risk allele.

Source

Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility

Díaz-Muñoz C, Bozzarelli I, Lopera-Maya EA, Belbasis L, Lo Faro V, Camargo Tavares L, Heredia-Fernández F, Di Lorenzo B, Sinha T, Esteban Blanco C, Favé MJ, Awadalla P

and 5 more — show all

Walters RG, Bonfiglio F, Zhernakova A, Sanna S, D'Amato M

Gut · 2026 · PMID 41558814 · open access

Questions about rs56074694

What is rs56074694?

rs56074694 is a single position in the genome, in or near the near HMGA2 gene. Published research associates it with stool frequency. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs56074694 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56074694 come from?

GWAS Catalog, Gut 2026, PMID:41558814. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Stool frequency (rs56074694). MyGeneLog™. https://www.mygenelog.com/variants/rs56074694

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