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Who was studied 516,865 European ancestry individuals.
The effect
Each copy of the C allele carried 1.01 times the odds of Irritable bowel syndrome (MTAG) (95% confidence interval 1.009-1.017); p = 3 × 10−10.
How common The C allele had a frequency of about 71% in the people studied.
Where it sits Chromosome 2, band 2q24.2 — in an intron of TANK-AS1.
What each result means
C/CTwo copies of the version the research linked to Irritable bowel syndrome (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Irritable bowel syndrome (MTAG). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Irritable bowel syndrome (MTAG). This is the starting point the study compared everyone against.
rs10184811 is a single position in the genome, in or near the TANK-AS1 gene. Published research associates it with irritable bowel syndrome (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10184811 linked to?
On MyGeneLog this position is linked to Irritable Bowel Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs10184811 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10184811 come from?
GWAS Catalog, Gut 2026, PMID:42425734. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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