4 5432328222228Reads by AI crawlersClaude3ChatGPT2Google · Gemini3Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others28Total54Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 4,533 European ancestry celiac disease cases, 5,539 European ancestry rheumatoid arthritis cases, 27,981 European ancestry controls; replicated in 2,169 European ancestry celiac disease cases, 2,845 European ancestry rheumatoid arthritis cases, 7,199 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 3 × 10−10.
Where it sits Chromosome 22, band 22q11.21 — a missense change in YDJC.
What each result means
C/CNo copy of the version the research linked to Celiac disease or Rheumatoid arthritis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Celiac disease or Rheumatoid arthritis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Celiac disease or Rheumatoid arthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2298428
What is rs2298428?
rs2298428 is a single position in the genome, in or near the UBE2L3 gene. Published research associates it with celiac disease or rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2298428 linked to?
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs2298428?
Subjects that appear in the title or abstract of the same papers as this rsID include gut and food intolerance (3 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2298428 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2298428 come from?
GWAS Catalog, PLoS Genet 2011, PMID:21383967. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 5432328222228Reads by AI crawlersClaude3ChatGPT2Google · Gemini3Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others28Total54Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Celiac disease or Rheumatoid arthritis (rs2298428). MyGeneLog™. https://www.mygenelog.com/variants/rs2298428