C/CPublished research associates this genotype with typical/baseline likelihood of Celiac disease or Rheumatoid arthritis — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2011, PMID:21383967)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Celiac disease or Rheumatoid arthritis. (GWAS Catalog, PLoS Genet 2011, PMID:21383967)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Celiac disease or Rheumatoid arthritis compared to the general population. (GWAS Catalog, PLoS Genet 2011, PMID:21383967)
rs2298428 is a single position in the genome, in or near the UBE2L3 gene. Published research associates it with celiac disease or rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2298428 linked to?
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs2298428 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2298428 come from?
GWAS Catalog, PLoS Genet 2011, PMID:21383967. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.