Sensitive

Celiac disease or Rheumatoid arthritis

TRAF1 · rs1953126

Where this position leads

Condition: Celiac Disease

rs1953126 Condition: Celiac Disease Celiac Disease Condition rs1953126 rs1953126 TRAF1

What the study found

Who was studied 4,533 European ancestry celiac disease cases, 5,539 European ancestry rheumatoid arthritis cases, 27,981 European ancestry controls; replicated in 2,169 European ancestry celiac disease cases, 2,845 European ancestry rheumatoid arthritis cases, 7,199 European ancestry controls.

The effect The reported allele is T; the catalogue records no effect size ; p = 4 × 10−11.

Where it sits Chromosome 9, band 9q33.2 — inside PHF19.

What each result means

C/C No copy of the version the research linked to Celiac disease or Rheumatoid arthritis. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Celiac disease or Rheumatoid arthritis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Celiac disease or Rheumatoid arthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1953126

What is rs1953126?

rs1953126 is a single position in the genome, in or near the TRAF1 gene. Published research associates it with celiac disease or rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1953126 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs1953126 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1953126 come from?

GWAS Catalog, PLoS Genet 2011, PMID:21383967. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Celiac disease or Rheumatoid arthritis (rs1953126). MyGeneLog™. https://www.mygenelog.com/variants/rs1953126

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