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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 11,489 European ancestry cases with celiac disease, 15,523 European ancestry cases with rheumatoid arthritis, 3,477 European ancestry cases with systemic sclerosis, 6,670 European ancestry cases with type 1 diabetes, 22,308 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 7 × 10−10.
Where it sits Chromosome 10, band 10p15.1 — between genes, 2.4 kb from RPL32P23.
What each result means
A/ATwo copies of the version the research linked to Autoimmune traits (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Autoimmune traits (pleiotropy). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Autoimmune traits (pleiotropy). This is the starting point the study compared everyone against.
Genome medicine · 2018 · PMID 30572963 · open access
Questions about rs72776098
What is rs72776098?
rs72776098 is a single position in the genome, in or near the IL2RA gene. Published research associates it with autoimmune traits (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs72776098 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72776098 come from?
GWAS Catalog, Genome medicine 2018, PMID:30572963. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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