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Gut microbiota abundance (k_Bacteria.p_Firmicutes.c_Negativicutes)

LINC00677 · rs2282037

Where this position leads

Condition: Gut Microbiota

rs2282037 Condition: Gut Microbiota Gut Microbiota Condition rs2282037 rs2282037 LINC00677

What the study found

Who was studied 7,738 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.102 lower (95% confidence interval 0.066-0.139); p = 4 × 10−8.

How common The T allele had a frequency of about 52% in the people studied.

Where it sits Chromosome 14, band 14q32.32 — in an intron of LINC00677.

What each result means

C/C No copy of the version the research linked to Gut microbiota abundance (k_Bacteria.p_Firmicutes.c_Negativicutes). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Gut microbiota abundance (k_Bacteria.p_Firmicutes.c_Negativicutes). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Gut microbiota abundance (k_Bacteria.p_Firmicutes.c_Negativicutes). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2282037

What is rs2282037?

rs2282037 is a single position in the genome, in or near the LINC00677 gene. Published research associates it with gut microbiota abundance (k_bacteria.p_firmicutes.c_negativicutes). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2282037 linked to?

On MyGeneLog this position is linked to Gut Microbiota. The research behind each link, and its sources, are set out on that condition page.

Does having rs2282037 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2282037 come from?

GWAS Catalog, Nature genetics 2022, PMID:35115690. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Gut microbiota abundance (k_Bacteria.p_Firmicutes.c_Negativicutes) (rs2282037). MyGeneLog™. https://www.mygenelog.com/variants/rs2282037

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