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16 matches for
Clarke TK.
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism
Luciano M,
Hagenaars SP,
Davies G,
Hill WD,
Clarke TK,
Shirali M,
Harris SE,
Marioni RE,
Liewald DC,
Fawns-Ritchie C,
Adams MJ,
Howard DM
and 4 more — show all
Nature genetics · 2018 · PMID 29255261
12 pages+
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
Howard DM,
Adams MJ,
Shirali M,
Clarke TK,
Marioni RE,
Davies G,
Coleman JRI,
Alloza C,
Shen X,
Barbu MC,
Wigmore EM,
Gibson J
and 9 more — show all
23andMe Research Team
Nature communications · 2018 · PMID 29662059 · open access
12 pages+
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
Howard DM,
Adams MJ,
Clarke TK,
Hafferty JD,
Gibson J,
Shirali M,
Coleman JRI,
Hagenaars SP,
Ward J,
Wigmore EM,
Alloza C,
Shen X
and 26 more — show all
Barbu MC,
Xu EY,
Whalley HC,
Marioni RE,
Porteous DJ,
Davies G,
Deary IJ,
Hemani G,
Berger K,
Teismann H,
Rawal R,
Arolt V,
Baune BT,
Dannlowski U,
Domschke K,
Tian C,
Hinds DA,
Trzaskowski M,
Byrne EM,
Ripke S,
Smith DJ,
Sullivan PF,
Wray NR,
Breen G,
Lewis CM,
McIntosh AM
23andMe Research Team · Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Nature neuroscience · 2019 · PMID 30718901
12 pages+
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits
Zhou H,
Sealock JM,
Sanchez-Roige S,
Clarke TK,
Levey DF,
Cheng Z,
Li B,
Polimanti R,
Kember RL,
Smith RV,
Thygesen JH,
Morgan MY
and 15 more — show all
Atkinson SR,
Thursz MR,
Nyegaard M,
Nyegaard M,
Mattheisen M,
Børglum AD,
Johnson EC,
Justice AC,
Palmer AA,
McQuillin A,
Davis LK,
Edenberg HJ,
Agrawal A,
Kranzler HR,
Gelernter J
Nature neuroscience · 2020 · PMID 32451486 · open access
12 pages+
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Mullins N,
Forstner AJ,
O'Connell KS,
Coombes B,
Coleman JRI,
Qiao Z,
Als TD,
Bigdeli TB,
Børte S,
Bryois J,
Charney AW,
Drange OK
and 305 more — show all
Gandal MJ,
Hagenaars SP,
Ikeda M,
Kamitaki N,
Kim M,
Krebs K,
Panagiotaropoulou G,
Schilder BM,
Sloofman LG,
Steinberg S,
Trubetskoy V,
Winsvold BS,
Won HH,
Abramova L,
Adorjan K,
Agerbo E,
Al Eissa M,
Albani D,
Alliey-Rodriguez N,
Anjorin A,
Antilla V,
Antoniou A,
Awasthi S,
Baek JH,
Bækvad-Hansen M,
Bass N,
Bauer M,
Beins EC,
Bergen SE,
Birner A,
Bøcker Pedersen C,
Bøen E,
Boks MP,
Bosch R,
Brum M,
Brumpton BM,
Brunkhorst-Kanaan N,
Budde M,
Bybjerg-Grauholm J,
Byerley W,
Cairns M,
Casas M,
Cervantes P,
Clarke TK,
Cruceanu C,
Cuellar-Barboza A,
Cunningham J,
Curtis D,
Czerski PM,
Dale AM,
Dalkner N,
David FS,
Degenhardt F,
Djurovic S,
Dobbyn AL,
Douzenis A,
Elvsåshagen T,
Escott-Price V,
Ferrier IN,
Fiorentino A,
Foroud TM,
Forty L,
Frank J,
Frei O,
Freimer NB,
Frisén L,
Gade K,
Garnham J,
Gelernter J,
Giørtz Pedersen M,
Gizer IR,
Gordon SD,
Gordon-Smith K,
Greenwood TA,
Grove J,
Guzman-Parra J,
Ha K,
Haraldsson M,
Hautzinger M,
Heilbronner U,
Hellgren D,
Herms S,
Hoffmann P,
Holmans PA,
Huckins L,
Jamain S,
Johnson JS,
Kalman JL,
Kamatani Y,
Kennedy JL,
Kittel-Schneider S,
Knowles JA,
Kogevinas M,
Koromina M,
Kranz TM,
Kranzler HR,
Kubo M,
Kupka R,
Kushner SA,
Lavebratt C,
Lawrence J,
Leber M,
Lee HJ,
Lee PH,
Levy SE,
Lewis C,
Liao C,
Lucae S,
Lundberg M,
MacIntyre DJ,
Magnusson SH,
Maier W,
Maihofer A,
Malaspina D,
Maratou E,
Martinsson L,
Mattheisen M,
McCarroll SA,
McGregor NW,
McGuffin P,
McKay JD,
Medeiros H,
Medland SE,
Millischer V,
Montgomery GW,
Moran JL,
Morris DW,
Mühleisen TW,
O'Brien N,
O'Donovan C,
Olde Loohuis LM,
Oruc L,
Papiol S,
Pardiñas AF,
Perry A,
Pfennig A,
Porichi E,
Potash JB,
Quested D,
Raj T,
Rapaport MH,
DePaulo JR,
Regeer EJ,
Rice JP,
Rivas F,
Rivera M,
Roth J,
Roussos P,
Ruderfer DM,
Sánchez-Mora C,
Schulte EC,
Senner F,
Sharp S,
Shilling PD,
Sigurdsson E,
Sirignano L,
Slaney C,
Smeland OB,
Smith DJ,
Sobell JL,
Søholm Hansen C,
Soler Artigas M,
Spijker AT,
Stein DJ,
Strauss JS,
Świątkowska B,
Terao C,
Thorgeirsson TE,
Toma C,
Tooney P,
Tsermpini EE,
Vawter MP,
Vedder H,
Walters JTR,
Witt SH,
Xi S,
Xu W,
Yang JMK,
Young AH,
Young H,
Zandi PP,
Zhou H,
Zillich L,
Adolfsson R,
Agartz I,
Alda M,
Alfredsson L,
Babadjanova G,
Backlund L,
Baune BT,
Bellivier F,
Bengesser S,
Berrettini WH,
Blackwood DHR,
Boehnke M,
Børglum AD,
Breen G,
Carr VJ,
Catts S,
Corvin A,
Craddock N,
Dannlowski U,
Dikeos D,
Esko T,
Etain B,
Ferentinos P,
Frye M,
Fullerton JM,
Gawlik M,
Gershon ES,
Goes FS,
Green MJ,
Grigoroiu-Serbanescu M,
Hauser J,
Henskens F,
Hillert J,
Hong KS,
Hougaard DM,
Hultman CM,
Hveem K,
Iwata N,
Jablensky AV,
Jones I,
Jones LA,
Kahn RS,
Kelsoe JR,
Kirov G,
Landén M,
Leboyer M,
Lewis CM,
Li QS,
Lissowska J,
Lochner C,
Loughland C,
Martin NG,
Mathews CA,
Mayoral F,
McElroy SL,
McIntosh AM,
McMahon FJ,
Melle I,
Michie P,
Milani L,
Mitchell PB,
Morken G,
Mors O,
Mortensen PB,
Mowry B,
Müller-Myhsok B,
Myers RM,
Neale BM,
Nievergelt CM,
Nordentoft M,
Nöthen MM,
O'Donovan MC,
Oedegaard KJ,
Olsson T,
Owen MJ,
Paciga SA,
Pantelis C,
Pato C,
Pato MT,
Patrinos GP,
Perlis RH,
Posthuma D,
Ramos-Quiroga JA,
Reif A,
Reininghaus EZ,
Ribasés M,
Rietschel M,
Ripke S,
Rouleau GA,
Saito T,
Schall U,
Schalling M,
Schofield PR,
Schulze TG,
Scott LJ,
Scott RJ,
Serretti A,
Shannon Weickert C,
Smoller JW,
Stefansson H,
Stefansson K,
Stordal E,
Streit F,
Sullivan PF,
Turecki G,
Vaaler AE,
Vieta E,
Vincent JB,
Waldman ID,
Weickert TW,
Werge T,
Wray NR,
Zwart JA,
Biernacka JM,
Nurnberger JI,
Cichon S,
Edenberg HJ,
Stahl EA,
McQuillin A,
Di Florio A,
Ophoff RA,
Andreassen OA
HUNT All-In Psychiatry
Nature genetics · 2021 · PMID 34002096 · open access
12 pages+
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)
Clarke TK,
Adams MJ,
Davies G,
Howard DM,
Hall LS,
Padmanabhan S,
Murray AD,
Smith BH,
Campbell A,
Hayward C,
Porteous DJ,
Deary IJ
and 1 more — show all
Molecular psychiatry · 2017 · PMID 28937693 · open access
11 pages
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Wray NR,
Ripke S,
Mattheisen M,
Trzaskowski M,
Byrne EM,
Abdellaoui A,
Adams MJ,
Agerbo E,
Air TM,
Andlauer TMF,
Bacanu SA,
Bækvad-Hansen M
and 205 more — show all
Beekman AFT,
Bigdeli TB,
Binder EB,
Blackwood DRH,
Bryois J,
Buttenschøn HN,
Bybjerg-Grauholm J,
Cai N,
Castelao E,
Christensen JH,
Clarke TK,
Coleman JIR,
Colodro-Conde L,
Couvy-Duchesne B,
Craddock N,
Crawford GE,
Crowley CA,
Dashti HS,
Davies G,
Deary IJ,
Degenhardt F,
Derks EM,
Direk N,
Dolan CV,
Dunn EC,
Eley TC,
Eriksson N,
Escott-Price V,
Kiadeh FHF,
Finucane HK,
Forstner AJ,
Frank J,
Gaspar HA,
Gill M,
Giusti-Rodríguez P,
Goes FS,
Gordon SD,
Grove J,
Hall LS,
Hannon E,
Hansen CS,
Hansen TF,
Herms S,
Hickie IB,
Hoffmann P,
Homuth G,
Horn C,
Hottenga JJ,
Hougaard DM,
Hu M,
Hyde CL,
Ising M,
Jansen R,
Jansen R,
Jin F,
Jorgenson E,
Knowles JA,
Kohane IS,
Kraft J,
Kretzschmar WW,
Krogh J,
Kutalik Z,
Lane JM,
Li Y,
Li Y,
Lind PA,
Liu X,
Lu L,
MacIntyre DJ,
MacKinnon DF,
Maier RM,
Maier W,
Marchini J,
Mbarek H,
McGrath P,
McGuffin P,
Medland SE,
Mehta D,
Middeldorp CM,
Mihailov E,
Milaneschi Y,
Milani L,
Mill J,
Mondimore FM,
Montgomery GW,
Mostafavi S,
Mullins N,
Nauck M,
Ng B,
Nivard MG,
Nyholt DR,
O'Reilly PF,
Oskarsson H,
Owen MJ,
Painter JN,
Pedersen CB,
Pedersen MG,
Peterson RE,
Pettersson E,
Peyrot WJ,
Pistis G,
Posthuma D,
Purcell SM,
Quiroz JA,
Qvist P,
Rice JP,
Riley BP,
Rivera M,
Saeed Mirza S,
Saxena R,
Schoevers R,
Schulte EC,
Shen L,
Shi J,
Shyn SI,
Sigurdsson E,
Sinnamon GBC,
Smit JH,
Smith DJ,
Stefansson H,
Steinberg S,
Stockmeier CA,
Streit F,
Strohmaier J,
Tansey KE,
Teismann H,
Teumer A,
Thompson W,
Thomson PA,
Thorgeirsson TE,
Tian C,
Traylor M,
Treutlein J,
Trubetskoy V,
Uitterlinden AG,
Umbricht D,
Van der Auwera S,
van Hemert AM,
Viktorin A,
Visscher PM,
Wang Y,
Webb BT,
Weinsheimer SM,
Wellmann J,
Willemsen G,
Witt SH,
Wu Y,
Xi HS,
Yang J,
Zhang F,
Arolt V,
Baune BT,
Berger K,
Boomsma DI,
Cichon S,
Dannlowski U,
de Geus ECJ,
DePaulo JR,
Domenici E,
Domschke K,
Esko T,
Grabe HJ,
Hamilton SP,
Hayward C,
Heath AC,
Hinds DA,
Kendler KS,
Kloiber S,
Lewis G,
Li QS,
Lucae S,
Madden PFA,
Magnusson PK,
Martin NG,
McIntosh AM,
Metspalu A,
Mors O,
Mortensen PB,
Müller-Myhsok B,
Nordentoft M,
Nöthen MM,
O'Donovan MC,
Paciga SA,
Pedersen NL,
Penninx BWJH,
Perlis RH,
Porteous DJ,
Potash JB,
Preisig M,
Rietschel M,
Schaefer C,
Schulze TG,
Smoller JW,
Stefansson K,
Tiemeier H,
Uher R,
Völzke H,
Weissman MM,
Werge T,
Winslow AR,
Lewis CM,
Levinson DF,
Breen G,
Børglum AD,
Sullivan PF
eQTLGen · 23andMe and 1 more consortia
Nature genetics · 2018 · PMID 29700475 · open access
10 pages
New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders
Evangelou E,
Gao H,
Chu C,
Ntritsos G,
Ntritsos G,
Blakeley P,
Butts AR,
Pazoki R,
Suzuki H,
Koskeridis F,
Yiorkas AM,
Karaman I
and 88 more — show all
Elliott J,
Luo Q,
Aeschbacher S,
Bartz TM,
Baumeister SE,
Braund PS,
Brown MR,
Brody JA,
Clarke TK,
Dimou N,
Faul JD,
Homuth G,
Jackson AU,
Kentistou KA,
Joshi PK,
Lemaitre RN,
Lind PA,
Lyytikäinen LP,
Mangino M,
Milaneschi Y,
Nelson CP,
Nolte IM,
Perälä MM,
Polasek O,
Porteous D,
Ratliff SM,
Smith JA,
Stančáková A,
Teumer A,
Tuominen S,
Thériault S,
Vangipurapu J,
Whitfield JB,
Wood A,
Yao J,
Yu B,
Zhao W,
Zhao W,
Arking DE,
Auvinen J,
Liu C,
Männikkö M,
Risch L,
Rotter JI,
Snieder H,
Veijola J,
Blakemore AI,
Boehnke M,
Campbell H,
Conen D,
Eriksson JG,
Grabe HJ,
Guo X,
van der Harst P,
Hartman CA,
Hayward C,
Heath AC,
Jarvelin MR,
Kähönen M,
Kardia SLR,
Kühne M,
Kuusisto J,
Laakso M,
Lahti J,
Lehtimäki T,
McIntosh AM,
Mohlke KL,
Morrison AC,
Martin NG,
Oldehinkel AJ,
Penninx BWJH,
Psaty BM,
Raitakari OT,
Rudan I,
Samani NJ,
Scott LJ,
Spector TD,
Verweij N,
Weir DR,
Wilson JF,
Levy D,
Tzoulaki I,
Bell JD,
Matthews PM,
Rothenfluh A,
Desrivières S,
Schumann G,
Elliott P
Nature human behaviour · 2019 · PMID 31358974
9 pages
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts
Sanchez-Roige S,
Palmer AA,
Fontanillas P,
Elson SL,
Adams MJ,
Howard DM,
Edenberg HJ,
Davies G,
Crist RC,
Deary IJ,
McIntosh AM,
Clarke TK
23andMe Research Team, the Substance Use Disorder Working Group of the Psychiatric Genomics Consortium
The American journal of psychiatry · 2019 · PMID 30336701
6 pages
Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl EA,
Breen G,
Forstner AJ,
McQuillin A,
Ripke S,
Trubetskoy V,
Mattheisen M,
Wang Y,
Coleman JRI,
Gaspar HA,
de Leeuw CA,
Steinberg S
and 265 more — show all
Pavlides JMW,
Trzaskowski M,
Byrne EM,
Pers TH,
Holmans PA,
Richards AL,
Abbott L,
Agerbo E,
Akil H,
Albani D,
Alliey-Rodriguez N,
Als TD,
Anjorin A,
Antilla V,
Awasthi S,
Badner JA,
Bækvad-Hansen M,
Barchas JD,
Bass N,
Bauer M,
Belliveau R,
Bergen SE,
Pedersen CB,
Bøen E,
Boks MP,
Boocock J,
Budde M,
Bunney W,
Burmeister M,
Bybjerg-Grauholm J,
Byerley W,
Casas M,
Cerrato F,
Cervantes P,
Chambert K,
Charney AW,
Chen D,
Churchhouse C,
Clarke TK,
Coryell W,
Craig DW,
Cruceanu C,
Curtis D,
Czerski PM,
Dale AM,
de Jong S,
Degenhardt F,
Del-Favero J,
DePaulo JR,
Djurovic S,
Dobbyn AL,
Dumont A,
Elvsåshagen T,
Escott-Price V,
Fan CC,
Fischer SB,
Flickinger M,
Foroud TM,
Forty L,
Frank J,
Fraser C,
Freimer NB,
Frisén L,
Gade K,
Gage D,
Garnham J,
Giambartolomei C,
Pedersen MG,
Goldstein J,
Gordon SD,
Gordon-Smith K,
Green EK,
Green MJ,
Greenwood TA,
Grove J,
Guan W,
Guzman-Parra J,
Hamshere ML,
Hautzinger M,
Heilbronner U,
Herms S,
Hipolito M,
Hoffmann P,
Holland D,
Huckins L,
Jamain S,
Johnson JS,
Juréus A,
Kandaswamy R,
Karlsson R,
Kennedy JL,
Kittel-Schneider S,
Knowles JA,
Kogevinas M,
Koller AC,
Kupka R,
Lavebratt C,
Lawrence J,
Lawson WB,
Leber M,
Lee PH,
Levy SE,
Li JZ,
Liu C,
Lucae S,
Maaser A,
MacIntyre DJ,
Mahon PB,
Maier W,
Martinsson L,
McCarroll S,
McGuffin P,
McInnis MG,
McKay JD,
Medeiros H,
Medland SE,
Meng F,
Milani L,
Montgomery GW,
Morris DW,
Mühleisen TW,
Mullins N,
Nguyen H,
Nievergelt CM,
Adolfsson AN,
Nwulia EA,
O'Donovan C,
Loohuis LMO,
Ori APS,
Oruc L,
Ösby U,
Perlis RH,
Perry A,
Pfennig A,
Potash JB,
Purcell SM,
Regeer EJ,
Reif A,
Reinbold CS,
Rice JP,
Rivas F,
Rivera M,
Roussos P,
Ruderfer DM,
Ryu E,
Sánchez-Mora C,
Schatzberg AF,
Scheftner WA,
Schork NJ,
Shannon Weickert C,
Shehktman T,
Shilling PD,
Sigurdsson E,
Slaney C,
Smeland OB,
Sobell JL,
Søholm Hansen C,
Spijker AT,
St Clair D,
Steffens M,
Strauss JS,
Streit F,
Strohmaier J,
Szelinger S,
Thompson RC,
Thorgeirsson TE,
Treutlein J,
Vedder H,
Wang W,
Watson SJ,
Weickert TW,
Witt SH,
Xi S,
Xu W,
Young AH,
Zandi P,
Zhang P,
Zöllner S,
Adolfsson R,
Agartz I,
Alda M,
Backlund L,
Baune BT,
Bellivier F,
Berrettini WH,
Biernacka JM,
Blackwood DHR,
Boehnke M,
Børglum AD,
Corvin A,
Craddock N,
Daly MJ,
Dannlowski U,
Esko T,
Etain B,
Frye M,
Fullerton JM,
Gershon ES,
Gill M,
Goes F,
Grigoroiu-Serbanescu M,
Hauser J,
Hougaard DM,
Hultman CM,
Jones I,
Jones LA,
Kahn RS,
Kirov G,
Landén M,
Leboyer M,
Lewis CM,
Li QS,
Lissowska J,
Martin NG,
Mayoral F,
McElroy SL,
McIntosh AM,
McMahon FJ,
Melle I,
Metspalu A,
Mitchell PB,
Morken G,
Mors O,
Mortensen PB,
Müller-Myhsok B,
Myers RM,
Neale BM,
Nimgaonkar V,
Nordentoft M,
Nöthen MM,
O'Donovan MC,
Oedegaard KJ,
Owen MJ,
Paciga SA,
Pato C,
Pato MT,
Posthuma D,
Ramos-Quiroga JA,
Ribasés M,
Rietschel M,
Rouleau GA,
Schalling M,
Schofield PR,
Schulze TG,
Serretti A,
Smoller JW,
Stefansson H,
Stefansson K,
Stordal E,
Sullivan PF,
Turecki G,
Vaaler AE,
Vieta E,
Vincent JB,
Werge T,
Nurnberger JI,
Wray NR,
Di Florio A,
Edenberg HJ,
Cichon S,
Ophoff RA,
Scott LJ,
Andreassen OA,
Kelsoe J,
Sklar P
eQTLGen Consortium · BIOS Consortium and 1 more consortia
Nature genetics · 2019 · PMID 31043756 · open access
6 pages
Minimal phenotyping yields genome-wide association signals of low specificity for major depression
Cai N,
Revez JA,
Adams MJ,
Andlauer TFM,
Breen G,
Byrne EM,
Clarke TK,
Forstner AJ,
Grabe HJ,
Hamilton SP,
Levinson DF,
Lewis CM
and 21 more — show all
Lewis G,
Martin NG,
Milaneschi Y,
Mors O,
Müller-Myhsok B,
Penninx BWJH,
Perlis RH,
Pistis G,
Potash JB,
Potash JB,
Preisig M,
Shi J,
Smoller JW,
Streit F,
Tiemeier H,
Uher R,
Van der Auwera S,
Viktorin A,
Weissman MM,
Kendler KS,
Flint J
MDD Working Group of the Psychiatric Genomics Consortium
Nature genetics · 2020 · PMID 32231276
6 pages
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
Schumann G,
Liu C,
O'Reilly P,
Gao H,
Song P,
Xu B,
Ruggeri B,
Amin N,
Jia T,
Preis S,
Segura Lepe M,
Akira S
and 115 more — show all
Barbieri C,
Baumeister S,
Cauchi S,
Clarke TK,
Enroth S,
Fischer K,
Hällfors J,
Harris SE,
Hieber S,
Hofer E,
Hottenga JJ,
Johansson Å,
Joshi PK,
Kaartinen N,
Laitinen J,
Lemaitre R,
Loukola A,
Luan J,
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