Links from this page to related variants, conditions, drugs and topics are not included for automated readers. Those connections are the Gene Knowledge Graph and are licensed as data: https://www.mygenelog.com/license
1 31217123213Reads by AI crawlersClaude2ChatGPT0Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others13Total31Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
3 / 4
Its strongest genetic-study result is p = 10−242, with 111 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
How common each version is
CT
KoreanKorea1K
C 100.0% · T 0.1%
World gnomAD
C 87.9% · T 12.1%
World 1000 Genomes
C 93.7% · T 6.3%
World TOPMed
C 87.4% · T 12.6%
By ancestry gnomAD
East Asian
C 99.8%
European (non-Finnish)
C 82.0% · T 18.0%
African / African American
C 96.6% · T 3.4%
South Asian
C 96.4% · T 3.6%
Admixed American (Latino)
C 86.3% · T 13.7%
Middle Eastern
C 76.4% · T 23.6%
Finnish
C 90.5% · T 9.5%
Ashkenazi Jewish
C 68.2% · T 31.8%
The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study. The ancestry rows are gnomAD's own groups (via Ensembl), as the survey defines them, not races.
What each result means
C/CTwo copies of the version the research linked to Depression. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Depression. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Depression. This is the starting point the study compared everyone against.
1 31217123213Reads by AI crawlersClaude2ChatGPT0Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others13Total31Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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