2 39216222222Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total39Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 13,493 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 1.34 lower (95% confidence interval 1.09-1.59); p = 6 × 10−26.
How common The T allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 6, band 6p22.3 — in an intron of TPMT.
What each result means
C/CNo copy of the version the research linked to Intrinsic epigenetic age acceleration. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Intrinsic epigenetic age acceleration. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Intrinsic epigenetic age acceleration. That is the strongest link of the three results. A link in a study is not a diagnosis.
PLoS genetics · 2019 · PMID 31738745 · open access
Questions about rs76244256
What is rs76244256?
rs76244256 is a single position in the genome, in or near the TPMT gene. Published research associates it with intrinsic epigenetic age acceleration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76244256 linked to?
On MyGeneLog this position is linked to Telomere Length and Epigenetic Age Acceleration. The research behind each link, and its sources, are set out on that condition page.
Does rs76244256 affect how medicines work?
TPMT carries pharmacogenomic findings for Thiopurines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs76244256 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76244256 come from?
GWAS Catalog, PLoS Genet 2019, PMID:31738745. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 39216222222Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total39Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Intrinsic epigenetic age acceleration (rs76244256). MyGeneLog™. https://www.mygenelog.com/variants/rs76244256