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Intrinsic epigenetic age acceleration

near NHLRC1 · rs7744541

What the study found

Who was studied 13,493 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.439 higher (95% confidence interval 0.33-0.55); p = 2 × 10−15.

How common The A allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 6, band 6p22.3 — between genes, 16 kb from NHLRC1.

What each result means

A/A Two copies of the version the research linked to Intrinsic epigenetic age acceleration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Intrinsic epigenetic age acceleration. That is a smaller link than two copies.
T/T No copy of the version the research linked to Intrinsic epigenetic age acceleration. This is the starting point the study compared everyone against.
Source

Questions about rs7744541

What is rs7744541?

rs7744541 is a single position in the genome, in or near the near NHLRC1 gene. Published research associates it with intrinsic epigenetic age acceleration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7744541 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7744541 come from?

GWAS Catalog, PLoS genetics 2019, PMID:31738745. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Intrinsic epigenetic age acceleration (rs7744541). MyGeneLog™. https://www.mygenelog.com/variants/rs7744541

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