Standard

Alcohol consumption

VRK2 · rs10496076

Where this position leads

Condition: Alcohol Consumption

rs10496076 Condition: Alcohol Consumption Alcohol Consumption Condition rs10496076 rs10496076 VRK2

What the study found

Who was studied 480,842 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.007 lower (95% confidence interval 0.005-0.009); p = 1 × 10−11.

How common The T allele had a frequency of about 37% in the people studied.

Where it sits Chromosome 2, band 2p16.1 — between genes, 49.1 kb from ACTG1P22.

What each result means

C/C No copy of the version the research linked to Alcohol consumption. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Alcohol consumption. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Alcohol consumption. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10496076

What is rs10496076?

rs10496076 is a single position in the genome, in or near the VRK2 gene. Published research associates it with alcohol consumption. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10496076 linked to?

On MyGeneLog this position is linked to Alcohol Consumption. The research behind each link, and its sources, are set out on that condition page.

Does having rs10496076 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10496076 come from?

GWAS Catalog, Nature human behaviour 2019, PMID:31358974. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alcohol consumption (rs10496076). MyGeneLog™. https://www.mygenelog.com/variants/rs10496076

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