Sensitive

Depression (broad)

SGIP1 · rs6679379

Where this position leads

Condition: Depression (Self-Reported Symptoms)

rs6679379 Condition: Depression (Self-Reported Symptoms) Depression (Self-Reported Symptoms) Condition rs6679379 rs6679379 SGIP1

What the study found

Who was studied 113,769 British ancestry cases, 208,811 British ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0072 higher (95% confidence interval 0.0047-0.0097); p = 3 × 10−8.

How common The T allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 1, band 1p31.3 — in an intron of SGIP1.

What each result means

C/C No copy of the version the research linked to Depression (broad). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Depression (broad). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Depression (broad). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6679379

What is rs6679379?

rs6679379 is a single position in the genome, in or near the SGIP1 gene. Published research associates it with depression (broad). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6679379 linked to?

On MyGeneLog this position is linked to Depression (Self-Reported Symptoms). The research behind each link, and its sources, are set out on that condition page.

Does having rs6679379 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6679379 come from?

GWAS Catalog, Nat Commun 2018, PMID:29662059. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Depression (broad) (rs6679379). MyGeneLog™. https://www.mygenelog.com/variants/rs6679379

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