Why this topic Vaping made quitting a live question again for a generation that never smoked.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
Counted in Europe PMC, where the title or abstract names both this topic and that rsID. The number is papers, not evidence of a cause.
CHRNA3
Smoking behavior
69 papers →BDNF
Smoking behavior
9 papers →CHRNA5
Smoking behavior
8 papers →CHRNA5
Lung cancer
8 papers →OPRM1
Opioid receptor sensitivity
7 papers →CYP2A6
Smoking behavior
4 papers →AGR3
Urinary albumin excretion
4 papers →CYP2A6
Local histogram emphysema pattern
4 papers →ADH1B
Alcohol metabolism speed
3 papers →DBH
Smoking behavior
3 papers →CHRNA3
Post bronchodilator FEV1
2 papers →TERT
Lung adenocarcinoma
2 papers →TERT
Serum prostate-specific antigen levels
2 papers →ALDH2
Alcohol flush reaction
2 papers →RAB4B-EGLN2
Nicotine metabolite ratio in current smokers
1 paper →FTO
Obesity
1 paper →CHRNA5
Local histogram emphysema pattern
1 paper →ZDHHC11
Pancreatic cancer
1 paper →CLPTM1L
Lung adenocarcinoma
1 paper →APOE
Lewy body disease
1 paper →CHRNA5
Post bronchodilator FEV1/FVC ratio
1 paper →Europe PMC, title and abstract only, searched for “smoking cessation”, “nicotine dependence”, “smoking initiation” alongside each published rsID. Full text was not counted: it returns every paper with an rsID buried in a supplementary table. Recounted monthly.
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Smoking and vaping. MyGeneLog™. https://www.mygenelog.com/topics/smoking
Smoking and vaping is this site's topic page for nicotine genetics — including why quitting is partly a metabolic question, not just a willpower one.
Partly. How hard quitting is turns out to be partly a metabolic question — how fast someone breaks down nicotine shapes dependence and withdrawal — though a co-mention here does not measure any one person's odds.
Vaping made quitting a live question again for a generation that never smoked a cigarette, reviving research questions about nicotine dependence that once seemed settled.
Europe PMC is searched for smoking cessation, nicotine dependence or smoking initiation appearing in a paper's title or abstract alongside a published rsID, recounted every month.