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Nicotine metabolite ratio in current smokers

RAB4B-EGLN2 · rs11878604

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Nicotine metabolite ratio in current smokers compared to the general population. (GWAS Catalog, Cancer Res 2016, PMID:27488534)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Nicotine metabolite ratio in current smokers. (GWAS Catalog, Cancer Res 2016, PMID:27488534)
T/T Published research associates this genotype with typical/baseline likelihood of Nicotine metabolite ratio in current smokers — no copies of the reported risk allele. (GWAS Catalog, Cancer Res 2016, PMID:27488534)

Source: GWAS Catalog, Cancer Res 2016, PMID:27488534

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11878604

What is rs11878604?

rs11878604 is a single position in the genome, in or near the RAB4B-EGLN2 gene. Published research associates it with nicotine metabolite ratio in current smokers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs11878604?

Subjects that appear in the title or abstract of the same papers as this rsID include smoking and vaping (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11878604 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11878604 come from?

GWAS Catalog, Cancer Res 2016, PMID:27488534. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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