7 5032636122223Reads by AI crawlersClaude3ChatGPT2Google · Gemini6Perplexity3Meta AI6Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 31,266 European ancestry individuals; replicated in 54,731 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.39 CPD higher (95% confidence interval 0.27-0.51); p = 2 × 10−12.
How common The C allele had a frequency of about 70% in the people studied.
Where it sits Chromosome 19, band 19q13.2 — between genes, 2.3 kb from CYP2A6.
What each result means
C/CTwo copies of the version the research linked to Smoking behavior. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Smoking behavior. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Smoking behavior. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs4105144
What is rs4105144?
rs4105144 is a single position in the genome, in or near the CYP2A6 gene. Published research associates it with smoking behavior. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs4105144 affect how medicines work?
CYP2A6 carries pharmacogenomic findings for Smoking cessation medicines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
What do people read about alongside rs4105144?
Subjects that appear in the title or abstract of the same papers as this rsID include smoking and vaping (4 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs4105144 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4105144 come from?
GWAS Catalog, Nat Genet 2010, PMID:20418888. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
7 5032636122223Reads by AI crawlersClaude3ChatGPT2Google · Gemini6Perplexity3Meta AI6Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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