Standard

Urinary albumin excretion

AGR3 · rs4410790

Where this position leads

Condition: Kidney Function

rs4410790 Condition: Kidney Function Kidney Function Condition Topic: Caffeine and energy drinks Caffeine and energy drinks Topic Topic: Alcohol and the flush Alcohol and the flush Topic Topic: Blood sugar and insulin Blood sugar and insulin Topic rs4410790 rs4410790 AGR3

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 382,500 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.018 higher (95% confidence interval 0.015-0.021); p = 3 × 10−25.

How common The C allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 7, band 7p21.1 — in an intron of LOC101927609.

What each result means

C/C Two copies of the version the research linked to Urinary albumin excretion. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Urinary albumin excretion. That is a smaller link than two copies.
T/T No copy of the version the research linked to Urinary albumin excretion. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs4410790

What is rs4410790?

rs4410790 is a single position in the genome, in or near the AGR3 gene. Published research associates it with urinary albumin excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4410790 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs4410790?

Subjects that appear in the title or abstract of the same papers as this rsID include caffeine and energy drinks (9 papers), alcohol and the flush (5 papers), blood sugar and insulin (4 papers), smoking and vaping (4 papers), heart and circulation (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs4410790 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4410790 come from?

GWAS Catalog, Am J Hum Genet 2018, PMID:30220432. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Urinary albumin excretion (rs4410790). MyGeneLog™. https://www.mygenelog.com/variants/rs4410790

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