6 5132234222427Reads by AI crawlersClaude3ChatGPT2Google · Gemini2Perplexity3Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)4ByteDance (Doubao)4Others27Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 1,926 European ance other ancestry cases, 2,522 European and other ancestry controls; replicated in 332 European ancestry cases, 462 European ancestry controls, 2,181 European and other ancestry cases, 4,290 European and other ancestry controls.
The effect
Each copy of the C allele carried 1.30 times the odds of Lung cancer (95% confidence interval 1.23-1.37); p = 5 × 10−20.
How common The C allele had a frequency of about 34% in the people studied.
Where it sits Chromosome 15, band 15q25.1 — in an intron of HYKK.
What each result means
C/CTwo copies of the version the research linked to Lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Lung cancer. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Lung cancer. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs8034191
What is rs8034191?
rs8034191 is a single position in the genome, in or near the CHRNA5 gene. Published research associates it with lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs8034191 linked to?
On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs8034191?
Subjects that appear in the title or abstract of the same papers as this rsID include smoking and vaping (8 papers), alcohol and the flush (2 papers), allergies (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs8034191 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8034191 come from?
GWAS Catalog, Nature 2008, PMID:18385738. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
6 5132234222427Reads by AI crawlersClaude3ChatGPT2Google · Gemini2Perplexity3Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)4ByteDance (Doubao)4Others27Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Lung cancer (rs8034191). MyGeneLog™. https://www.mygenelog.com/variants/rs8034191