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Smoking behavior

CHRNA5 · rs2036527

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Smoking behavior compared to the general population. (GWAS Catalog, Transl Psychiatry 2012, PMID:22832964)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Smoking behavior. (GWAS Catalog, Transl Psychiatry 2012, PMID:22832964)

G/G Published research associates this genotype with typical/baseline likelihood of Smoking behavior — no copies of the reported risk allele. (GWAS Catalog, Transl Psychiatry 2012, PMID:22832964)

Source: GWAS Catalog, Transl Psychiatry 2012, PMID:22832964

Questions about rs2036527

What is rs2036527?

rs2036527 is a single position in the genome, in or near the CHRNA5 gene. Published research associates it with smoking behavior. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2036527 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2036527 come from?

GWAS Catalog, Transl Psychiatry 2012, PMID:22832964. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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