DBH · rs3025343
Where this position leads
Condition: Smoking Behaviour and Nicotine Dependence
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied Up to 74,035 European ancestry individuals; replicated in Up to 68,988 participants.
The effect Each copy of the G allele carried 1.12 times the odds of Smoking behavior (95% confidence interval 1.08-1.18); p = 4 × 10−8.
How common The G allele had a frequency of about 84% in the people studied.
Where it sits Chromosome 9, band 9q34.2 — between genes, 3.8 kb from FAM163B.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs3025343 is a single position in the genome, in or near the DBH gene. Published research associates it with smoking behavior. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Smoking Behaviour and Nicotine Dependence. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include smoking and vaping (3 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Genet 2010, PMID:20418890. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Smoking behavior (rs3025343). MyGeneLog™. https://www.mygenelog.com/variants/rs3025343