Sensitive

Lung adenocarcinoma

CLPTM1L · rs31489

Where this position leads

Condition: Lung Cancer

rs31489 Condition: Lung Cancer Lung Cancer Condition rs31489 rs31489 CLPTM1L

What the study found

Who was studied 5,739 European ancestry cases, 5,848 European ancestry controls; replicated in 7,561 European ancestry cases, 13,818 European ancestry controls.

The effect Each copy of the C allele carried 1.12 times the odds of Lung adenocarcinoma (95% confidence interval 1.09-1.16); p = 2 × 10−10.

How common The C allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 5, band 5p15.33 — in an intron of CLPTM1L.

What each result means

A/A No copy of the version the research linked to Lung adenocarcinoma. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Lung adenocarcinoma. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Lung adenocarcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs31489

What is rs31489?

rs31489 is a single position in the genome, in or near the CLPTM1L gene. Published research associates it with lung adenocarcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs31489 linked to?

On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs31489?

Subjects that appear in the title or abstract of the same papers as this rsID include smoking and vaping (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs31489 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs31489 come from?

GWAS Catalog, Am J Hum Genet 2009, PMID:19836008. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung adenocarcinoma (rs31489). MyGeneLog™. https://www.mygenelog.com/variants/rs31489

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