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14 matches for
Johnson E.
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
McKay JD,
Hung RJ,
Han Y,
Zong X,
Carreras-Torres R,
Christiani DC,
Caporaso NE,
Johansson M,
Xiao X,
Li Y,
Byun J,
Dunning A
and 128 more — show all
Pooley KA,
Qian DC,
Ji X,
Liu G,
Timofeeva MN,
Bojesen SE,
Wu X,
Le Marchand L,
Albanes D,
Bickeböller H,
Aldrich MC,
Bush WS,
Tardon A,
Rennert G,
Teare MD,
Field JK,
Kiemeney LA,
Lazarus P,
Haugen A,
Lam S,
Schabath MB,
Andrew AS,
Shen H,
Hong YC,
Yuan JM,
Bertazzi PA,
Pesatori AC,
Ye Y,
Diao N,
Su L,
Zhang R,
Brhane Y,
Leighl N,
Johansen JS,
Mellemgaard A,
Saliba W,
Haiman CA,
Wilkens LR,
Fernandez-Somoano A,
Fernandez-Tardon G,
van der Heijden HFM,
Kim JH,
Dai J,
Hu Z,
Davies MPA,
Marcus MW,
Brunnström H,
Manjer J,
Melander O,
Muller DC,
Overvad K,
Trichopoulou A,
Tumino R,
Doherty JA,
Barnett MP,
Chen C,
Goodman GE,
Cox A,
Taylor F,
Woll P,
Brüske I,
Wichmann HE,
Manz J,
Muley TR,
Risch A,
Rosenberger A,
Grankvist K,
Johansson M,
Shepherd FA,
Tsao MS,
Arnold SM,
Haura EB,
Bolca C,
Holcatova I,
Janout V,
Kontic M,
Lissowska J,
Mukeria A,
Ognjanovic S,
Orlowski TM,
Scelo G,
Swiatkowska B,
Zaridze D,
Bakke P,
Skaug V,
Zienolddiny S,
Duell EJ,
Butler LM,
Koh WP,
Gao YT,
Houlston RS,
McLaughlin J,
Stevens VL,
Joubert P,
Lamontagne M,
Nickle DC,
Obeidat M,
Timens W,
Zhu B,
Song L,
Kachuri L,
Artigas MS,
Tobin MD,
Wain LV,
Rafnar T,
Thorgeirsson TE,
Reginsson GW,
Stefansson K,
Hancock DB,
Bierut LJ,
Spitz MR,
Gaddis NC,
Lutz SM,
Gu F,
Johnson EO,
Kamal A,
Pikielny C,
Zhu D,
Lindströem S,
Jiang X,
Tyndale RF,
Chenevix-Trench G,
Beesley J,
Bossé Y,
Chanock S,
Brennan P,
Landi MT,
Amos CI
SpiroMeta Consortium
Nature genetics · 2017 · PMID 28604730 · open access
12 pages+
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
Liu M,
Jiang Y,
Wedow R,
Li Y,
Brazel DM,
Chen F,
Datta G,
Davila-Velderrain J,
McGuire D,
Tian C,
Zhan X,
Choquet H
and 111 more — show all
Docherty AR,
Faul JD,
Foerster JR,
Fritsche LG,
Gabrielsen ME,
Gordon SD,
Haessler J,
Hottenga JJ,
Huang H,
Jang SK,
Jansen PR,
Ling Y,
Mägi R,
Matoba N,
McMahon G,
Mulas A,
Orrù V,
Palviainen T,
Pandit A,
Reginsson GW,
Skogholt AH,
Smith JA,
Taylor AE,
Turman C,
Willemsen G,
Young H,
Young KA,
Zajac GJM,
Zhao W,
Zhou W,
Bjornsdottir G,
Boardman JD,
Boehnke M,
Boomsma DI,
Chen C,
Cucca F,
Davies GE,
Eaton CB,
Ehringer MA,
Esko T,
Fiorillo E,
Gillespie NA,
Gudbjartsson DF,
Haller T,
Harris KM,
Heath AC,
Hewitt JK,
Hickie IB,
Hokanson JE,
Hopfer CJ,
Hunter DJ,
Iacono WG,
Johnson EO,
Kamatani Y,
Kardia SLR,
Keller MC,
Kellis M,
Kooperberg C,
Kraft P,
Krauter KS,
Laakso M,
Lind PA,
Loukola A,
Lutz SM,
Madden PAF,
Martin NG,
McGue M,
McQueen MB,
Medland SE,
Metspalu A,
Mohlke KL,
Nielsen JB,
Okada Y,
Peters U,
Polderman TJC,
Posthuma D,
Reiner AP,
Rice JP,
Rimm E,
Rose RJ,
Runarsdottir V,
Stallings MC,
Stančáková A,
Stefansson H,
Thai KK,
Tindle HA,
Tyrfingsson T,
Wall TL,
Weir DR,
Weisner C,
Whitfield JB,
Winsvold BS,
Yin J,
Zuccolo L,
Bierut LJ,
Hveem K,
Lee JJ,
Munafò MR,
Saccone NL,
Willer CJ,
Cornelis MC,
David SP,
Hinds DA,
Jorgenson E,
Kaprio J,
Stitzel JA,
Stefansson K,
Thorgeirsson TE,
Abecasis G,
Liu DJ,
Vrieze S
23andMe Research Team · HUNT All-In Psychiatry
Nature genetics · 2019 · PMID 30643251 · open access
12 pages+
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits
Zhou H,
Sealock JM,
Sanchez-Roige S,
Clarke TK,
Levey DF,
Cheng Z,
Li B,
Polimanti R,
Kember RL,
Smith RV,
Thygesen JH,
Morgan MY
and 15 more — show all
Atkinson SR,
Thursz MR,
Nyegaard M,
Nyegaard M,
Mattheisen M,
Børglum AD,
Johnson EC,
Justice AC,
Palmer AA,
McQuillin A,
Davis LK,
Edenberg HJ,
Agrawal A,
Kranzler HR,
Gelernter J
Nature neuroscience · 2020 · PMID 32451486 · open access
12 pages+
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Karlsson Linnér R,
Mallard TT,
Barr PB,
Sanchez-Roige S,
Madole JW,
Driver MN,
Poore HE,
de Vlaming R,
Grotzinger AD,
Tielbeek JJ,
Johnson EC,
Liu M
and 17 more — show all
Rosenthal SB,
Ideker T,
Zhou H,
Kember RL,
Pasman JA,
Verweij KJH,
Liu DJ,
Vrieze S,
Kranzler HR,
Gelernter J,
Harris KM,
Tucker-Drob EM,
Waldman ID,
Palmer AA,
Harden KP,
Koellinger PD,
Dick DM
COGA Collaborators
Nature neuroscience · 2021 · PMID 34446935 · open access
12 pages+
Genetic diversity fuels gene discovery for tobacco and alcohol use
Saunders GRB,
Wang X,
Chen F,
Jang SK,
Liu M,
Wang C,
Gao S,
Jiang Y,
Khunsriraksakul C,
Otto JM,
Addison C,
Akiyama M
and 205 more — show all
Albert CM,
Aliev F,
Alonso A,
Arnett DK,
Ashley-Koch AE,
Ashrani AA,
Barnes KC,
Barr RG,
Bartz TM,
Becker DM,
Bielak LF,
Benjamin EJ,
Bis JC,
Bjornsdottir G,
Blangero J,
Bleecker ER,
Boardman JD,
Boerwinkle E,
Boomsma DI,
Boorgula MP,
Bowden DW,
Brody JA,
Cade BE,
Chasman DI,
Chavan S,
Chen YI,
Chen Z,
Cheng I,
Cho MH,
Choquet H,
Cole JW,
Cornelis MC,
Cucca F,
Curran JE,
de Andrade M,
Dick DM,
Docherty AR,
Duggirala R,
Eaton CB,
Ehringer MA,
Esko T,
Faul JD,
Fernandes Silva L,
Fiorillo E,
Fornage M,
Freedman BI,
Gabrielsen ME,
Garrett ME,
Gharib SA,
Gieger C,
Gillespie N,
Glahn DC,
Gordon SD,
Gu CC,
Gu D,
Gudbjartsson DF,
Guo X,
Haessler J,
Hall ME,
Haller T,
Harris KM,
He J,
Herd P,
Hewitt JK,
Hickie I,
Hidalgo B,
Hokanson JE,
Hopfer C,
Hottenga J,
Hou L,
Huang H,
Hung YJ,
Hunter DJ,
Hveem K,
Hwang SJ,
Hwu CM,
Iacono W,
Irvin MR,
Jee YH,
Johnson EO,
Joo YY,
Jorgenson E,
Justice AE,
Kamatani Y,
Kaplan RC,
Kaprio J,
Kardia SLR,
Keller MC,
Kelly TN,
Kooperberg C,
Korhonen T,
Kraft P,
Krauter K,
Kuusisto J,
Laakso M,
Lasky-Su J,
Lee WJ,
Lee JJ,
Levy D,
Li L,
Li K,
Li Y,
Lin K,
Lind PA,
Liu C,
Lloyd-Jones DM,
Lutz SM,
Ma J,
Mägi R,
Manichaikul A,
Martin NG,
Mathur R,
Matoba N,
McArdle PF,
McGue M,
McQueen MB,
Medland SE,
Metspalu A,
Meyers DA,
Millwood IY,
Mitchell BD,
Mohlke KL,
Moll M,
Montasser ME,
Morrison AC,
Mulas A,
Nielsen JB,
North KE,
Oelsner EC,
Okada Y,
Orrù V,
Palmer ND,
Palviainen T,
Pandit A,
Park SL,
Peters U,
Peters A,
Peyser PA,
Polderman TJC,
Rafaels N,
Redline S,
Reed RM,
Reiner AP,
Rice JP,
Rich SS,
Richmond NE,
Roan C,
Rotter JI,
Rueschman MN,
Runarsdottir V,
Saccone NL,
Schwartz DA,
Shadyab AH,
Shi J,
Shringarpure SS,
Sicinski K,
Skogholt AH,
Smith JA,
Smith NL,
Sotoodehnia N,
Stallings MC,
Stefansson H,
Stefansson K,
Stitzel JA,
Sun X,
Syed M,
Tal-Singer R,
Taylor AE,
Taylor KD,
Telen MJ,
Thai KK,
Tiwari H,
Turman C,
Tyrfingsson T,
Wall TL,
Walters RG,
Weir DR,
Weiss ST,
White WB,
Whitfield JB,
Wiggins KL,
Willemsen G,
Willer CJ,
Winsvold BS,
Xu H,
Yanek LR,
Yin J,
Young KL,
Young KA,
Yu B,
Zhao W,
Zhou W,
Zöllner S,
Zuccolo L,
Batini C,
Bergen AW,
Bierut LJ,
David SP,
Gagliano Taliun SA,
Hancock DB,
Jiang B,
Munafò MR,
Thorgeirsson TE,
Liu DJ,
Vrieze S
23andMe Research Team · Biobank Japan Project
Nature · 2022 · PMID 36477530 · open access
12 pages+
Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications
Levey DF,
Galimberti M,
Deak JD,
Wendt FR,
Bhattacharya A,
Koller D,
Harrington KM,
Quaden R,
Johnson EC,
Gupta P,
Biradar M,
Lam M
and 18 more — show all
Cooke M,
Rajagopal VM,
Empke SLL,
Zhou H,
Nunez YZ,
Kranzler HR,
Edenberg HJ,
Agrawal A,
Smoller JW,
Lencz T,
Hougaard DM,
Børglum AD,
Demontis D,
Gaziano JM,
Gandal MJ,
Polimanti R,
Stein MB,
Gelernter J
Veterans Affairs Million Veteran Program
Nature genetics · 2023 · PMID 37985822 · open access
8 pages
Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
Maihofer AX,
Choi KW,
Coleman JRI,
Daskalakis NP,
Denckla CA,
Ketema E,
Morey RA,
Polimanti R,
Ratanatharathorn A,
Torres K,
Wingo AP,
Zai CC
and 169 more — show all
Aiello AE,
Almli LM,
Amstadter AB,
Andersen SB,
Andreassen OA,
Arbisi PA,
Ashley-Koch AE,
Austin SB,
Avdibegović E,
Borglum AD,
Babić D,
Bækvad-Hansen M,
Baker DG,
Beckham JC,
Bierut LJ,
Bisson JI,
Boks MP,
Bolger EA,
Bradley B,
Brashear M,
Breen G,
Bryant RA,
Bustamante AC,
Bybjerg-Grauholm J,
Calabrese JR,
Caldas-de-Almeida JM,
Chen CY,
Dale AM,
Dalvie S,
Deckert J,
Delahanty DL,
Dennis MF,
Disner SG,
Domschke K,
Duncan LE,
Džubur Kulenović A,
Erbes CR,
Evans A,
Farrer LA,
Feeny NC,
Flory JD,
Forbes D,
Franz CE,
Galea S,
Garrett ME,
Gautam A,
Gelaye B,
Gelernter J,
Geuze E,
Gillespie CF,
Goçi A,
Gordon SD,
Guffanti G,
Hammamieh R,
Hauser MA,
Heath AC,
Hemmings SMJ,
Hougaard DM,
Jakovljević M,
Jett M,
Johnson EO,
Jones I,
Jovanovic T,
Qin XJ,
Karstoft KI,
Kaufman ML,
Kessler RC,
Khan A,
Kimbrel NA,
King AP,
Koen N,
Kranzler HR,
Kremen WS,
Lawford BR,
Lebois LAM,
Lewis C,
Liberzon I,
Linnstaedt SD,
Logue MW,
Lori A,
Lugonja B,
Luykx JJ,
Lyons MJ,
Maples-Keller JL,
Marmar C,
Martin NG,
Maurer D,
Mavissakalian MR,
McFarlane A,
McGlinchey RE,
McLaughlin KA,
McLean SA,
Mehta D,
Mellor R,
Michopoulos V,
Milberg W,
Miller MW,
Morris CP,
Mors O,
Mortensen PB,
Nelson EC,
Nordentoft M,
Norman SB,
O'Donnell M,
Orcutt HK,
Panizzon MS,
Peters ES,
Peterson AL,
Peverill M,
Pietrzak RH,
Polusny MA,
Rice JP,
Risbrough VB,
Roberts AL,
Rothbaum AO,
Rothbaum BO,
Roy-Byrne P,
Ruggiero KJ,
Rung A,
Rutten BPF,
Saccone NL,
Sanchez SE,
Schijven D,
Seedat S,
Seligowski AV,
Seng JS,
Sheerin CM,
Silove D,
Smith AK,
Smoller JW,
Sponheim SR,
Stein DJ,
Stevens JS,
Teicher MH,
Thompson WK,
Trapido E,
Uddin M,
Ursano RJ,
van den Heuvel LL,
Van Hooff M,
Vermetten E,
Vinkers CH,
Voisey J,
Wang Y,
Wang Z,
Werge T,
Williams MA,
Williamson DE,
Winternitz S,
Wolf C,
Wolf EJ,
Yehuda R,
Young KA,
Young RM,
Zhao H,
Zoellner LA,
Haas M,
Lasseter H,
Provost AC,
Salem RM,
Sebat J,
Shaffer RA,
Wu T,
Ripke S,
Daly MJ,
Ressler KJ,
Koenen KC,
Stein MB,
Nievergelt CM
Biological psychiatry · 2022 · PMID 34865855 · open access
3 pages
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders
Hatoum AS,
Colbert SMC,
Johnson EC,
Huggett SB,
Deak JD,
Pathak G,
Jennings MV,
Paul SE,
Karcher NR,
Hansen I,
Baranger DAA,
Edwards A
and 10 more — show all
Substance Use Disorder Working Group of the Psychiatric Genomics Consortium
Nature. Mental health · 2023 · PMID 37250466
3 pages
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
Quach BC,
Bray MJ,
Gaddis NC,
Liu M,
Palviainen T,
Minica CC,
Zellers S,
Sherva R,
Aliev F,
Nothnagel M,
Young KA,
Marks JA
and 34 more — show all
Young H,
Carnes MU,
Guo Y,
Waldrop A,
Sey NYA,
Landi MT,
McNeil DW,
Drichel D,
Farrer LA,
Markunas CA,
Vink JM,
Hottenga JJ,
Iacono WG,
Kranzler HR,
Saccone NL,
Neale MC,
Madden P,
Rietschel M,
Marazita ML,
McGue M,
Won H,
Winterer G,
Grucza R,
Dick DM,
Gelernter J,
Caporaso NE,
Baker TB,
Boomsma DI,
Kaprio J,
Hokanson JE,
Vrieze S,
Bierut LJ,
Johnson EO,
Hancock DB
Nature communications · 2020 · PMID 33144568 · open access
2 pages
Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes
Chen J,
Loukola A,
Gillespie NA,
Peterson R,
Jia P,
Riley B,
Maes H,
Dick DM,
Kendler KS,
Damaj MI,
Miles MF,
Zhao Z
and 34 more — show all
Li MD,
Vink JM,
Minica CC,
Willemsen G,
Boomsma DI,
Qaiser B,
Madden PAF,
Korhonen T,
Jousilahti P,
Hällfors J,
Gelernter J,
Kranzler HR,
Sherva R,
Farrer L,
Maher B,
Vanyukov M,
Taylor M,
Ware JJ,
Munafò MR,
Lutz SM,
Hokanson JE,
Gu F,
Landi MT,
Caporaso NE,
Hancock DB,
Gaddis NC,
Baker TB,
Bierut LJ,
Johnson EO,
Chenoweth M,
Lerman C,
Tyndale R,
Kaprio J,
Chen X
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020 · PMID 31294817
1 page
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
Nievergelt CM,
Maihofer AX,
Klengel T,
Atkinson EG,
Chen CY,
Choi KW,
Coleman JRI,
Dalvie S,
Duncan LE,
Gelernter J,
Levey DF,
Logue MW
and 167 more — show all
Polimanti R,
Provost AC,
Ratanatharathorn A,
Stein MB,
Torres K,
Aiello AE,
Almli LM,
Amstadter AB,
Andersen SB,
Andreassen OA,
Arbisi PA,
Ashley-Koch AE,
Austin SB,
Avdibegovic E,
Babić D,
Bækvad-Hansen M,
Baker DG,
Beckham JC,
Bierut LJ,
Bisson JI,
Boks MP,
Bolger EA,
Børglum AD,
Bradley B,
Brashear M,
Breen G,
Bryant RA,
Bustamante AC,
Bybjerg-Grauholm J,
Calabrese JR,
Caldas-de-Almeida JM,
Dale AM,
Daly MJ,
Daskalakis NP,
Deckert J,
Delahanty DL,
Dennis MF,
Disner SG,
Domschke K,
Dzubur-Kulenovic A,
Erbes CR,
Evans A,
Farrer LA,
Feeny NC,
Flory JD,
Forbes D,
Franz CE,
Galea S,
Garrett ME,
Gelaye B,
Geuze E,
Gillespie C,
Uka AG,
Gordon SD,
Guffanti G,
Hammamieh R,
Harnal S,
Hauser MA,
Heath AC,
Hemmings SMJ,
Hougaard DM,
Jakovljevic M,
Jett M,
Johnson EO,
Jones I,
Jovanovic T,
Qin XJ,
Junglen AG,
Karstoft KI,
Kaufman ML,
Kessler RC,
Khan A,
Kimbrel NA,
King AP,
Koen N,
Kranzler HR,
Kremen WS,
Lawford BR,
Lebois LAM,
Lewis CE,
Linnstaedt SD,
Lori A,
Lugonja B,
Luykx JJ,
Lyons MJ,
Maples-Keller J,
Marmar C,
Martin AR,
Martin NG,
Maurer D,
Mavissakalian MR,
McFarlane A,
McGlinchey RE,
McLaughlin KA,
McLean SA,
McLeay S,
Mehta D,
Milberg WP,
Miller MW,
Morey RA,
Morris CP,
Mors O,
Mortensen PB,
Neale BM,
Nelson EC,
Nordentoft M,
Norman SB,
O'Donnell M,
Orcutt HK,
Panizzon MS,
Peters ES,
Peterson AL,
Peverill M,
Pietrzak RH,
Polusny MA,
Rice JP,
Ripke S,
Risbrough VB,
Roberts AL,
Rothbaum AO,
Rothbaum BO,
Roy-Byrne P,
Ruggiero K,
Rung A,
Rutten BPF,
Saccone NL,
Sanchez SE,
Schijven D,
Seedat S,
Seligowski AV,
Seng JS,
Sheerin CM,
Silove D,
Smith AK,
Smoller JW,
Sponheim SR,
Stein DJ,
Stevens JS,
Sumner JA,
Teicher MH,
Thompson WK,
Trapido E,
Uddin M,
Ursano RJ,
van den Heuvel LL,
Van Hooff M,
Vermetten E,
Vinkers CH,
Voisey J,
Wang Y,
Wang Z,
Werge T,
Williams MA,
Williamson DE,
Winternitz S,
Wolf C,
Wolf EJ,
Wolff JD,
Yehuda R,
Young RM,
Young KA,
Zhao H,
Zoellner LA,
Liberzon I,
Ressler KJ,
Haas M,
Koenen KC
Nature communications · 2019 · PMID 31594949 · open access
1 page
Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes
Sherva R,
Zhu C,
Wetherill L,
Edenberg HJ,
Johnson E,
Degenhardt L,
Agrawal A,
Martin NG,
Nelson E,
Kranzler HR,
Gelernter J,
Farrer LA
Exploration of medicine · 2021 · PMID 34124712
1 page
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond
Gaddis N,
Mathur R,
Marks J,
Zhou L,
Quach B,
Waldrop A,
Levran O,
Agrawal A,
Randesi M,
Adelson M,
Jeffries PW,
Martin NG
and 36 more — show all
Degenhardt L,
Montgomery GW,
Wetherill L,
Lai D,
Bucholz K,
Foroud T,
Porjesz B,
Runarsdottir V,
Tyrfingsson T,
Einarsson G,
Gudbjartsson DF,
Webb BT,
Crist RC,
Kranzler HR,
Sherva R,
Zhou H,
Hulse G,
Wildenauer D,
Kelty E,
Attia J,
Holliday EG,
McEvoy M,
Scott RJ,
Schwab SG,
Maher BS,
Gruza R,
Kreek MJ,
Nelson EC,
Thorgeirsson T,
Stefansson K,
Berrettini WH,
Gelernter J,
Edenberg HJ,
Bierut L,
Hancock DB,
Johnson EO
Scientific reports · 2022 · PMID 36207451 · open access
1 page
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Why is my paper here? I never gave you permission.
Nothing of your paper is reproduced here. This page records that a MyGeneLog™ page
cites your work, and links to the paper on PubMed — which is what a citation is.
Your title and author list come from Europe PMC, the same public record a library
catalogue uses.
Why are all the authors listed instead of "et al."?
Because a study that needed 622 people is a different kind of study from one that
needed four, and "et al." erases that. Twelve names show and the rest are one click
away. Everyone is searchable, including the 187th name on a consortium paper —
that person exists and may be looking for it.
My name is misspelt, or the paper is wrong.
Tell us and it is fixed. Names come from the public record and initials are
inconsistent across databases; where two people share a form of a name we cannot
separate them, and we would rather be corrected than guess.
My paper is not here. Does that mean you rejected it?
No. This catalogue is assembled from what a small team could read, and it is
thinnest outside European-ancestry cohorts. A paper is absent because nobody has got
to it, not because it was assessed and turned down.
Which pages rest on a paper?
Each row lists them, up to six, and links to each one. The count beside a row is
how many pages cite it in total.
How often does this change?
It is rebuilt from the pages every hour. A paper appears the moment a page starts
resting on it and disappears if that page stops — there is no separate list to
keep in step, because the citation lives on the page that makes the claim.