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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 300,789 European ancestry problematic alcohol use individuals, 270,120 European ancestry problematic tobacco use individuals, 46,351 European ancestry cannabis use disorder individuals, 30,443 European ancestry opioid use disorder individuals.
The effect
Each copy of the G allele shifted the measure 0.014 higher; p = 2 × 10−9.
Where it sits Chromosome 14, band 14q32.33 — in an intron of PPP1R13B-DT.
What each result means
A/ANo copy of the version the research linked to Addiction risk factors. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Addiction risk factors. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Addiction risk factors. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs10083370 is a single position in the genome, in or near the PPP1R13B-DT gene. Published research associates it with addiction risk factors. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10083370 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10083370 come from?
GWAS Catalog, Nature. Mental health 2023, PMID:37250466. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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