Standard

Addiction risk factors

PLCL2 · rs55855024

What the study found

Who was studied 300,789 European ancestry problematic alcohol use individuals, 270,120 European ancestry problematic tobacco use individuals, 46,351 European ancestry cannabis use disorder individuals, 30,443 European ancestry opioid use disorder individuals.

The effect Each copy of the C allele shifted the measure 0.014 lower; p = 2 × 10−8.

Where it sits Chromosome 3, band 3p24.3 — in an intron of PLCL2.

What each result means

A/A No copy of the version the research linked to Addiction risk factors. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Addiction risk factors. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Addiction risk factors. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs55855024

What is rs55855024?

rs55855024 is a single position in the genome, in or near the PLCL2 gene. Published research associates it with addiction risk factors. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55855024 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55855024 come from?

GWAS Catalog, Nature. Mental health 2023, PMID:37250466. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Addiction risk factors (rs55855024). MyGeneLog™. https://www.mygenelog.com/variants/rs55855024

← See all variants